Familial isolated pituitary adenomas: from genetics to therapy (Q33713409)

28 July 2017

1 reference

title

Familial isolated pituitary adenomas: from genetics to therapy (English)

1 reference

28 July 2017

Federica Guaraldi

1

1 reference

PubMed ID

21348957

28 July 2017

Roberto Salvatori

series ordinal

2

1 reference

PubMed ID

21348957

28 July 2017

language of work or name

English

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publication date

1 February 2011

1 reference

Clinical and Translational Science

28 July 2017

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28 July 2017

4

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28 July 2017

1

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28 July 2017

55-62

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MEN-4 and other multiple endocrine neoplasias due to cyclin-dependent kinase inhibitors (p27(Kip1) and p18(INK4C)) mutations

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Mice with inactivation of aryl hydrocarbon receptor-interacting protein (Aip) display complete penetrance of pituitary adenomas with aberrant ARNT expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

PRKAR1A and the evolution of pituitary tumors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Functional studies of menin through genetic manipulation of the Men1 homolog in mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

The epidemiology and genetics of pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Aryl hydrocarbon receptor regulates cell cycle progression in human breast cancer cells via a functional interaction with cyclin-dependent kinase 4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Familial pituitary adenomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

G-protein and signalling in pituitary tumours

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Differential gene expression in models of pituitary prolactin-producing tumoral cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Mutations of the gene for the aryl hydrocarbon receptor-interacting protein in pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Acromegaly and gigantism in the medical literature. Case descriptions in the era before and the early years after the initial publication of Pierre Marie (1886)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

A hypomorphic allele of aryl hydrocarbon receptor-associated protein-9 produces a phenocopy of the AHR-null mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Pituitary tumors in childhood: update of diagnosis, treatment and molecular genetics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Wnt pathway inhibitors are strongly down-regulated in pituitary tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

The clinical, pathological, and genetic features of familial isolated pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Phosphodiesterase 2A forms a complex with the co-chaperone XAP2 and regulates nuclear translocation of the aryl hydrocarbon receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Carney complex: pathology and molecular genetics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Pituitary pathology in patients with Carney Complex: growth-hormone producing hyperplasia or tumors and their association with other abnormalities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Clinical characterization of familial isolated pituitary adenomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Minireview: PRKAR1A: normal and abnormal functions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

The prevalence of pituitary adenomas: a systematic review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Two distinct regions of the immunophilin-like protein XAP2 regulate dioxin receptor function and interaction with hsp90

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Isolated familial somatotropinomas: establishment of linkage to chromosome 11q13.1-11q13.3 and evidence for a potential second locus at chromosome 2p16-12

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Analysis of cyclin D1 (CCND1) allelic imbalance and overexpression in sporadic human pituitary tumors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Loss of heterozygosity on chromosome 11q13 in two families with acromegaly/gigantism is independent of mutations of the multiple endocrine neoplasia type I gene.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Results of treatment of pituitary disease in multiple endocrine neoplasia, type I.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Mutation and cancer: statistical study of retinoblastoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

[Prolactin adenoma in a irl whose mother had had a pituitary adenoma with amenorrhea-galactorrhea].

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Association of the Ah receptor with the 90-kDa heat shock protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Clonal origin of pituitary adenomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Prevalence of pituitary adenomas: a community-based, cross-sectional study in Banbury (Oxfordshire, UK).

28 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Pituitary adenoma predisposition caused by germline mutations in the AIP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Genetic, molecular and clinical features of familial isolated pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Molecular genetics of the aip gene in familial pituitary tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein - The role of hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

The tyrosine kinase receptor RET interacts in vivo with aryl hydrocarbon receptor-interacting protein to alter survivin availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Genome-wide scan identifies novel modifier loci of acromegalic phenotypes for isolated familial somatotropinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Isolated familial somatotropinomas: clinical features and analysis of the MEN1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Pituitary Tumor Transforming Gene (PTTG) Expression in Pituitary Adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Expression of pituitary tumour-derived, N-terminally truncated isoform of fibroblast growth factor receptor 4 (ptd-FGFR4) correlates with tumour invasiveness but not with G-protein alpha subunit (gsp) mutation in human GH-secreting pituitary adenoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Reduced expression levels of the cell-cycle inhibitor p27Kip1 in human pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Expression of p18(INK4C) is down-regulated in human pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Promoter hypermethylation profile of cell cycle regulator genes in pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Frequent loss of the CDKN2C (p18INK4c) gene product in pituitary adenomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

ZAC1 target genes and pituitary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Aggressive pituitary adenomas occurring in young patients in a large Polynesian kindred with a germline R271W mutation in the AIP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Variable pathological and clinical features of a large Brazilian family harboring a mutation in the aryl hydrocarbon receptor-interacting protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Genetics of pituitary adenomas: current theories and future implications

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia

30 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Aryl hydrocarbon receptor interacting protein(AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1752-8062.2010.00254.X

Loss of Expression ofGADD45γ, a Growth Inhibitory Gene, in Human Pituitary Adenomas: Implications for Tumorigenesis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439841

Germline inactivating mutations of the aryl hydrocarbon receptor-interacting protein gene in a large cohort of sporadic acromegaly: mutations are found in a subset of young patients with macroadenomas

30 October 2018

1 reference

12 December 2020

Ras mutations in human pituitary tumors

1 reference

12 December 2020

Isolated familial somatotropinoma

1 reference

12 December 2020

Preferential loss of Death Associated Protein kinase expression in invasive pituitary tumours is associated with either CpG island methylation or homozygous deletion

1 reference

12 December 2020

Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma

1 reference

12 December 2020

Tumor deletion mapping on chromosome 11q13 in eight families with isolated familial somatotropinoma and in 15 sporadic somatotropinomas

1 reference

12 December 2020

Mutations in theAryl Hydrocarbon Receptor Interacting ProteinGene Are Not Highly Prevalent among Subjects with Sporadic Pituitary Adenomas

1 reference

12 December 2020

Analysis of the MEN1 gene in sporadic pituitary adenomas

1 reference

12 December 2020

Invasive human pituitary tumors express a point-mutated alpha-protein kinase-C

1 reference

12 December 2020

Inactivation of the tumor suppressor gene on 11q13 in brothers with familial acrogigantism without multiple endocrine neoplasia type 1

1 reference

12 December 2020

Allelic deletion in pituitary adenomas reflects aggressive biological activity and has potential value as a prognostic marker

1 reference

12 December 2020

The aryl hydrocarbon receptor-interacting protein gene is rarely mutated in sporadic GH-secreting adenomas

1 reference

12 December 2020

P53 gene mutations in pituitary carcinomas

1 reference

12 December 2020

10.1111/J.1752-8062.2010.00254.X

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

21348957