Phosphatases reverse p53-mediated cell cycle checkpoints (Q33665426)

28 July 2017

Phosphatases reverse p53-mediated cell cycle checkpoints (English)

1 reference

28 July 2017

Lawrence A Donehower

1

1 reference

PubMed ID

24808140

28 July 2017

language of work or name

English

0 references

publication date

7 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

1 reference

28 July 2017

111

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28 July 2017

7172-7173

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28 July 2017

20

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Distinct phosphatases antagonize the p53 response in different phases of the cell cycle

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Mutational heterogeneity in cancer and the search for new cancer-associated genes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Overexpression of protein phosphatase 4 correlates with poor prognosis in patients with stage II pancreatic ductal adenocarcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Posttranslational modification of p53: cooperative integrators of function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Gene amplification and overexpression of protein phosphatase 1alpha in oral squamous cell carcinoma cell lines.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Cancer. p53, guardian of the genome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034213

Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response

14 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1405663111

Protein phosphatase PP4 is overexpressed in human breast and lung tumors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24808140

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1405663111

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

24808140