Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies. (Q33659691)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904582%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Characterization of Novel PI3Kδ Inhibitors as Potential Therapeutics for SLE and Lupus Nephritis in Pre-Clinical Studies (English)

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20 March 2020

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2

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20 March 2020

author name string

Philipp Haselmayer

1

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20 March 2020

Mathilde Muzerelle

3

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20 March 2020

Samer El Bawab

4

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20 March 2020

Caroline Waltzinger

5

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20 March 2020

Lisa Bruns

6

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20 March 2020

Nada Abla

7

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20 March 2020

Mark A Polokoff

8

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20 March 2020

Carole Jond-Necand

9

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20 March 2020

Marilène Gaudet

10

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20 March 2020

Audrey Benoit

11

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20 March 2020

Dominique Bertschy Meier

12

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20 March 2020

Catherine Martin

13

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20 March 2020

Denise Gretener

14

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20 March 2020

Maria Stella Lombardi

15

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20 March 2020

Roland Grenningloh

16

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20 March 2020

Christoph Ladel

17

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20 March 2020

Jørgen Søberg Petersen

18

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20 March 2020

Pascale Gaillard

19

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20 March 2020

Hong Ji

20

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20 March 2020

publication date

22 May 2014

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20 March 2020

published in

Frontiers in Immunology

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20 March 2020

volume

5

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20 March 2020

page(s)

233

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T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?

20 March 2020

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Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation

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IFN-α confers resistance of systemic lupus erythematosus nephritis to therapy in NZB/W F1 mice

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Interferon-α induces unabated production of short-lived plasma cells in pre-autoimmune lupus-prone (NZB×NZW)F1 mice but not in BALB/c mice

21 June 2018

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PI3Ks in lymphocyte signaling and development

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Review: Lupus nephritis: pathologic features, epidemiology and a guide to therapeutic decisions.

21 June 2018

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Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis

21 June 2018

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Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

21 June 2018

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Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys

21 June 2018

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Taming the PI3K team to hold inflammation and cancer at bay.

21 June 2018

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PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

21 June 2018

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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

21 June 2018

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SLE: challenges and candidates in human disease

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21 June 2018

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21 June 2018

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21 June 2018

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A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

21 June 2018

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21 June 2018

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Systemic lupus erythematosus.

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Enhanced phosphoinositide 3-kinase δ activity is a frequent event in systemic lupus erythematosus that confers resistance to activation-induced T cell death.

21 January 2018

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

21 January 2018

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Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells

21 January 2018

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Relevance of systemic lupus erythematosus nephritis animal models to human disease

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12 December 2020

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Identifiers

DOI

10.3389/FIMMU.2014.00233

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904582%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24904582%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

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