Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis (Q33657413)

28 July 2017

Selective roles of E2Fs for ErbB2- and Myc-mediated mammary tumorigenesis (English)

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28 July 2017

L Wu

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28 July 2017

A de Bruin

2

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28 July 2017

H Wang

3

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28 July 2017

T Simmons

4

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28 July 2017

W Cleghorn

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28 July 2017

L E Goldenberg

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28 July 2017

E Sites

7

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28 July 2017

A Sandy

8

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28 July 2017

A Trimboli

9

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28 July 2017

S A Fernandez

10

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28 July 2017

C Eng

11

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28 July 2017

C Shapiro

12

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28 July 2017

G Leone

13

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28 July 2017

language of work or name

English

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publication date

25 November 2013

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28 July 2017

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34

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1

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28 July 2017

119-128

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https://scigraph.springernature.com/pub.10.1038/onc.2013.511

28 July 2017

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cites work

Cancer statistics, 2013

1 reference

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Hallmarks of Cancer: The Next Generation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2F2 suppresses Myc-induced proliferation and tumorigenesis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

A role for E2F activities in determining the fate of Myc-induced lymphomagenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Expression analysis of 6p22 genomic gain in retinoblastoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

The E2F transcriptional network: old acquaintances with new faces

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Conditional E2F1 activation in transgenic mice causes testicular atrophy and dysplasia mimicking human CIS.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2F target genes: unraveling the biology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Amplification and overexpression of E2F3 in human bladder cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2F-3B is a physiological target of cyclin A

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Sibling rivalry in the E2F family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

The E2F1-3 transcription factors are essential for cellular proliferation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Specific protection against breast cancers by cyclin D1 ablation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

The Rb/E2F pathway and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Molecular genetics of prostate cancer.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Identification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

E2f3 is critical for normal cellular proliferation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Generalized lacZ expression with the ROSA26 Cre reporter strain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

The regulation of E2F by pRB-family proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Cre-mediated gene deletion in the mammary gland

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Nuclear overexpression of the E2F3 transcription factor in human lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

E2F3 amplification and overexpression is associated with invasive tumor growth and rapid tumor cell proliferation in urinary bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

E2F3a stimulates proliferation, p53-independent apoptosis and carcinogenesis in a transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

High incidence of thymic epithelial tumors in E2F2 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032808

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Conditional deletion of Rb causes early stage prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Expression of the E2F family in human gastrointestinal carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Overexpression of E2F-1 in lung and liver metastases of human colon cancer is associated with gene amplification

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Dual functions of E2F-1 in a transgenic mouse model of liver carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Myc requires distinct E2F activities to induce S phase and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Prediction and genetic demonstration of a role for activator E2Fs in Myc-induced tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.511

Toward an understanding of the functional complexity of the E2F and retinoblastoma families

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24276244

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2013.511

1 reference

Dimensions Publication ID

28 July 2017

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28 July 2017

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