Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy (Q33648539)

28 July 2017

Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy (English)

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28 July 2017

7

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Daniel Metzger

object named as

Daniel Metzger

6

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Robert G Oshima

8

object named as

Robert G Oshima

1 reference

28 July 2017

Lili Cheng

1

1 reference

28 July 2017

Jianfei Guo

2

1 reference

28 July 2017

Liguang Sun

3

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28 July 2017

Jian Fu

4

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28 July 2017

Peter F Barnes

5

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28 July 2017

Takashi Amagai

9

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28 July 2017

Dong-Ming Su

10

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28 July 2017

language of work or name

English

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publication date

2 December 2009

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Journal of Biological Chemistry

28 July 2017

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28 July 2017

285

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28 July 2017

8

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28 July 2017

5836-5847

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A roadmap for thymic epithelial cell development.

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Genetic mechanisms in Apc-mediated mammary tumorigenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Cytokines, leptin, and stress-induced thymic atrophy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Clinical strategies to enhance T cell reconstitution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

A central role for central tolerance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Thymic microenvironments for T cell differentiation and selection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Molecular defects in T- and B-cell primary immunodeficiency diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Learning from nudity: lessons from the nude phenotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Many roads, one destination for T cell progenitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Regulation of immunity by self-reactive T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Impaired apoptosis and immune senescence - cause or effect?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Insights into thymic aging and regeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Forkhead-box transcription factors and their role in the immune system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Ancestral founder mutation of the nude (FOXN1) gene in congenital severe combined immunodeficiency associated with alopecia in southern Italy population

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Rapid generation of inducible mouse mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Expression of conditional cre recombinase in epithelial tissues of transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Development of alphabeta T cells in the human thymus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Analysis of thymic stromal cell populations using flow cytometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Thymus medulla consisting of epithelial islets each derived from a single progenitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Temporally and spatially regulated somatic mutagenesis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Characterization of mouse and human nude genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

The whn transcription factor encoded by the nude locus contains an evolutionarily conserved and functionally indispensable activation domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Two subsets of epithelial cells in the thymic medulla

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

21 June 2018

The thymus of Nu/+ mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Two genetically separable steps in the differentiation of thymic epithelium.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Exposing the human nude phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Formation of a functional thymus initiated by a postnatal epithelial progenitor cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Transgenic expression of cyclin D1 in thymic epithelial precursors promotes epithelial and T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Features of medullary thymic epithelium implicate postnatal development in maintaining epithelial heterogeneity and tissue-restricted antigen expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.072124

NFS/N-nu/ + mice can macroscopically be distinguished from NFS/N- +/+ littermates by their thymic size and shape.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820809

Checkpoints in the development of thymic cortical epithelial cells

30 October 2018

1 reference

12 December 2020

A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation

1 reference

12 December 2020

Epithelial heterogeneity in the murine thymus: fucose-specific lectins bind medullary epithelial cells

1 reference

12 December 2020

Molecular characterization of the mouse involuted thymus: aberrations in expression of transcription regulators in thymocyte and epithelial compartments

1 reference

12 December 2020

Cutting edge: thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus

1 reference

12 December 2020

Expression of Dll4 and CCL25 in Foxn1-negative epithelial cells in the post-natal thymus

1 reference

12 December 2020

Back to the beginning--the quest for thymic epithelial stem cells

1 reference

12 December 2020

Lymphohematopoietic progenitors do not have a synchronized defect with age-related thymic involution

1 reference

12 December 2020

The aged thymus shows normal recruitment of lymphohematopoietic progenitors but has defects in thymic epithelial cells

1 reference

12 December 2020

FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.072124

1 reference

28 July 2017

1 reference

28 July 2017

1 reference