Modulation of mdm2 pre-mRNA splicing by 9-aminoacridine-PNA (peptide nucleic acid) conjugates targeting intron-exon junctions (Q33621929)

28 July 2017

Modulation of mdm2 pre-mRNA splicing by 9-aminoacridine-PNA (peptide nucleic acid) conjugates targeting intron-exon junctions (English)

1 reference

28 July 2017

1 reference

Takehiko Shiraishi

1

1 reference

28 July 2017

Jonhard Eysturskarth

series ordinal

2

1 reference

28 July 2017

Peter E Nielsen

series ordinal

3

1 reference

28 July 2017

language of work or name

English

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publication date

30 June 2010

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28 July 2017

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28 July 2017

10

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28 July 2017

342

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https://scigraph.springernature.com/pub.10.1186/1471-2407-10-342

28 July 2017

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cites work

Improved cellular activity of antisense peptide nucleic acids by conjugation to a cationic peptide-lipid (CatLip) domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Enhanced delivery of cell-penetrating peptide-peptide nucleic acid conjugates by endosomal disruption

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Systemic delivery of antisense oligoribonucleotide restores dystrophin expression in body-wide skeletal muscles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Modification of alternative splicing by antisense therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Restoration of human beta-globin gene expression in murine and human IVS2-654 thalassemic erythroid cells by free uptake of antisense oligonucleotides.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Alternative and aberrant splicing of MDM2 mRNA in human cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Control of alternative splicing by antisense oligonucleotides as a potential chemotherapy: effects on gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Antisense-induced exon skipping restores dystrophin expression in DMD patient derived muscle cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

p76(MDM2) inhibits the ability of p90(MDM2) to destabilize p53.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

The MDM2 gene amplification database

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle.

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Induction of exon skipping of the dystrophin transcript in lymphoblastoid cells by transfecting an antisense oligodeoxynucleotide complementary to an exon recognition sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Modification of alternative splicing pathways as a potential approach to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Improved cell-penetrating peptide-PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-342

Tumor promotion by Mdm2 splice variants unable to bind p53.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Ubiquitous induction of p53 in tumor cells by antisense inhibition of MDM2 expression.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910690

Solid-phase synthesis of peptide nucleic acids

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20591158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antisense morpholino oligonucleotide analog induces missplicing of C-myc mRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20591158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-10-342

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference