The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients (Q33604936)

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English	The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients	scientific article

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients (English)

1 reference

Europe PubMed Central

28 July 2017

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hypermethylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

object named as

Pinpin Lin

3

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author name string

Ruo-Kai Lin

1

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Europe PubMed Central

28 July 2017

Yi-Shuan Hsieh

2

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Europe PubMed Central

28 July 2017

Han-Shui Hsu

4

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Europe PubMed Central

28 July 2017

Chih-Yi Chen

5

1 reference

Europe PubMed Central

28 July 2017

Yen-An Tang

6

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Europe PubMed Central

28 July 2017

Chung-Fan Lee

7

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Europe PubMed Central

28 July 2017

Yi-Ching Wang

8

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

19 January 2010

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Europe PubMed Central

28 July 2017

Journal of Clinical Investigation

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Europe PubMed Central

28 July 2017

120

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Europe PubMed Central

28 July 2017

2

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Europe PubMed Central

28 July 2017

521-532

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Europe PubMed Central

28 July 2017

Mutations and response to epidermal growth factor receptor inhibitors

1 reference

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28 July 2018

Epigenetic changes in Alzheimer's disease: decrements in DNA methylation

1 reference

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Alterations of DNA methylation and clinicopathological diversity of human cancers

1 reference

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28 July 2018

Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosis

1 reference

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28 July 2018

Reviewing the role of DNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

28 July 2018

Understanding tobacco smoke carcinogen NNK and lung tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

28 July 2018

Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer.

1 reference

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28 July 2018

Epigenetics in human disease and prospects for epigenetic therapy

1 reference

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28 July 2018

DNA methyltransferase 1 knock down induces gene expression by a mechanism independent of DNA methylation and histone deacetylation

1 reference

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28 July 2018

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

28 July 2018

Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention.

1 reference

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28 July 2018

Focus on lung cancer

1 reference

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28 July 2018

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

1 reference

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28 July 2018

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

1 reference

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28 July 2018

GSK3 takes centre stage more than 20 years after its discovery

1 reference

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28 July 2018

p16INK4a and beta-catenin alterations in rat liver tumors induced by NNK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

28 July 2018

Hyperhomocysteinemia, DNA methylation and vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Phosphatidylinositol 3-kinase/protein kinase B pathway stabilizes DNA methyltransferase I protein and maintains DNA methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Aberrant methylation of the FHIT gene in chronic smokers with early stage squamous cell carcinoma of the lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Shutting down Wnt signal-activated cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810088

30 October 2018

Increased expression of hepatic DNA methyltransferase in smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer epigenetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene promoter hypermethylation in mouse lung tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093774

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI40706

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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