Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor (Q33599508)

28 July 2017

Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor (English)

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28 July 2017

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Ruben Abagyan

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Nicholas T Crump

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Nicholas T Crump

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Rhoda M Alani

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Rhoda M Alani

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author name string

Erin M Bowers

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28 July 2017

Gai Yan

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28 July 2017

Chandrani Mukherjee

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28 July 2017

Andrew Orry

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28 July 2017

Ling Wang

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28 July 2017

Marc A Holbert

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28 July 2017

Catherine A Hazzalin

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28 July 2017

Glen Liszczak

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28 July 2017

Hua Yuan

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28 July 2017

Cecilia Larocca

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28 July 2017

S Adrian Saldanha

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28 July 2017

Yan Sun

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28 July 2017

David J Meyers

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28 July 2017

Ronen Marmorstein

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28 July 2017

Louis C Mahadevan

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28 July 2017

Philip A Cole

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1 May 2010

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28 July 2017

Chemistry and Biology

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28 July 2017

17

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5

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28 July 2017

471-482

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describes a project that uses

28 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2884008/fullTextXML

inferred from PubMed Central ID database lookup

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Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP

14 July 2018

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The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

14 July 2018

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14 July 2018

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14 July 2018

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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

14 July 2018

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14 July 2018

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Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

14 July 2018

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Regulation of the p300 HAT domain via a novel activation loop.

14 July 2018

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14 July 2018

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Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex

14 July 2018

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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

14 July 2018

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The CBP co-activator is a histone acetyltransferase

14 July 2018

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14 July 2018

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

14 July 2018

1 reference

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Fluorescent markers for hypoxic cells. A study of novel heterocyclic compounds that undergo bio-reductive binding

14 July 2018

1 reference

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Mechanism of p300 specific histone acetyltransferase inhibition by small molecules

14 July 2018

1 reference

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General strategy for the synthesis of natural and unnatural dialkylmaleic anhydrides

30 October 2018

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Discovery of new Gram-negative antivirulence drugs: structure and properties of novel E. coli WaaC inhibitors.

30 October 2018

1 reference

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Discovery of novel chemotypes to a G-protein-coupled receptor through ligand-steered homology modeling and structure-based virtual screening.

30 October 2018

1 reference

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Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.

30 October 2018

1 reference

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Bisubstrate inhibition: Theory and application to N-acetyltransferases.

30 October 2018

1 reference

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p300 is required for orderly G1/S transition in human cancer cells.

30 October 2018

1 reference

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Characterization of the yeast trimeric-SAS acetyltransferase complex

30 October 2018

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Small molecule modulators of histone acetyltransferase p300.

30 October 2018

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Dantrolene analogues revisited: general synthesis and specific functions capable of discriminating two kinds of Ca2+ release from sarcoplasmic reticulum of mouse skeletal muscle.

30 October 2018

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Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity

30 October 2018

1 reference

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Highly Modular Synthesis ofC1-Symmetric Aminosulfoximines and Their Use as Ligands in Copper-Catalyzed Asymmetric Mukaiyama-Aldol Reactions

30 October 2018

1 reference

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Extraction, purification and analysis of histones

30 October 2018

1 reference

12 December 2020

Synthesis and evaluation of a potent and selective cell-permeable p300 histone acetyltransferase inhibitor

1 reference

12 December 2020

p300/CBP-associated factor histone acetyltransferase processing of a peptide substrate. Kinetic analysis of the catalytic mechanism

1 reference

12 December 2020

A continuous, nonradioactive assay for histone acetyltransferases

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12 December 2020

10.1016/J.CHEMBIOL.2010.03.006

Identifiers

DOI

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28 July 2017

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28 July 2017

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