Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma (Q33592948)

28 July 2017

Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma (English)

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28 July 2017

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Benjamin G Barwick

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author name string

Robert C Castellino

1

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28 July 2017

Matthew Schniederjan

3

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28 July 2017

Meghan C Buss

4

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28 July 2017

Oren Becher

5

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28 July 2017

Dolores Hambardzumyan

6

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28 July 2017

Tobey J Macdonald

7

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28 July 2017

Daniel J Brat

8

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28 July 2017

Donald L Durden

9

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28 July 2017

language of work or name

English

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publication date

26 May 2010

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28 July 2017

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28 July 2017

5

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28 July 2017

5

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28 July 2017

e10849

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Creative Commons Attribution 4.0 International

28 July 2017

start time

26 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice

14 July 2018

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Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth

14 July 2018

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PTEN-deficient cancers depend on PIK3CB.

14 July 2018

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14 July 2018

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Hedgehog signalling in vascular development

14 July 2018

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PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

14 July 2018

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Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors

14 July 2018

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Targeting phosphoinositide 3-kinase: moving towards therapy

14 July 2018

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Overexpressed TP73 induces apoptosis in medulloblastoma

14 July 2018

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BRCA2 is required for neurogenesis and suppression of medulloblastoma

14 July 2018

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Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

14 July 2018

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Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway

14 July 2018

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Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN.

14 July 2018

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Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region

14 July 2018

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Current treatment of medulloblastoma: recent advances and future challenges

14 July 2018

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HB-EGF is a potent inducer of tumor growth and angiogenesis

14 July 2018

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Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

14 July 2018

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Regulation of neuroD2 expression in mouse brain

14 July 2018

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Medulloblastoma: present concepts of stratification into risk groups

14 July 2018

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14 July 2018

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14 July 2018

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Classifying the medulloblastoma: insights from morphology and molecular genetics

14 July 2018

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14 July 2018

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14 July 2018

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Significance analysis of microarrays applied to the ionizing radiation response

14 July 2018

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PTEN controls tumor-induced angiogenesis

14 July 2018

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14 July 2018

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14 July 2018

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Pale islands in medulloblastoma consist of differentiated cells with low growth potential.

14 July 2018

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Treatment of early childhood medulloblastoma by postoperative chemotherapy alone

28 July 2018

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The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.

21 January 2018

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Microvessel density is a prognostic indicator for patients with astroglial brain tumors.

21 January 2018

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Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumours.

21 January 2018

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High microvessel density in primitive neuroectodermal brain tumors of childhood.

21 January 2018

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21 January 2018

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Apoptosis suppression by somatic cell transfer of Bcl-2 promotes Sonic hedgehog-dependent medulloblastoma formation in mice.

21 January 2018

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Medulloblastoma tumorigenesis diverges from cerebellar granule cell differentiation in patched heterozygous mice

21 January 2018

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Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN.

21 January 2018

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10.1371/JOURNAL.PONE.0010849

30 October 2018

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DOI

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28 July 2017

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28 July 2017

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