Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways (Q33588231)

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English	Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways	scientific article

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways (English)

1 reference

Europe PubMed Central

28 July 2017

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

Lavanya Reddivari

object named as

Lavanya Reddivari

2

0 references

Sridhar Radhakrishnan

object named as

Sridhar Radhakrishnan

3

0 references

author name string

Jairam Vanamala

1

1 reference

Europe PubMed Central

28 July 2017

Chris Tarver

4

1 reference

Europe PubMed Central

28 July 2017

language of work or name

0 references

publication date

26 May 2010

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

10

1 reference

Europe PubMed Central

28 July 2017

238

1 reference

Europe PubMed Central

28 July 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-10-238

0 references

Obesity-enhanced colon cancer: functional food compounds and their mechanisms of action

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Genomic and epigenetic instability in colorectal cancer pathogenesis

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14 July 2018

Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention

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Involvement of FKHRL1 in melanoma cell survival and death.

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Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

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14 July 2018

Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3

1 reference

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14 July 2018

Resveratrol-induced apoptosis is associated with activation of p53 and inhibition of protein translation in T47D human breast cancer cells

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Anthocyanin fraction from potato extracts is cytotoxic to prostate cancer cells through activation of caspase-dependent and caspase-independent pathways.

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The many ways of Wnt in cancer

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Resveratrol improves health and survival of mice on a high-calorie diet

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Wnt/beta-catenin signaling in development and disease

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Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells

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Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells

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Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells

1 reference

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14 July 2018

Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins

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Resveratrol inhibits insulin responses in a SirT1-independent pathway

1 reference

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The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines

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Suppression of colon carcinogenesis by bioactive compounds in grapefruit

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Influence of obesity on the risk of developing colon cancer

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14 July 2018

The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells

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p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

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Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1.

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Free insulin-like growth factors -- measurements and relationships to growth hormone secretion and glucose homeostasis

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The MDM2-p53 interaction.

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14 July 2018

Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum

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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression

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The insulin-like growth factor system and cancer

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A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells

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Prevalence and Trends in Obesity Among US Adults, 1999-2000

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Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol

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Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1.

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20504360

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10.1186/1471-2407-10-238

1 reference

Europe PubMed Central

28 July 2017

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1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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