Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans (Q33580154)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

Protein unc-112 CELE_C47E8.7

10 March 2020

main subject

Caenorhabditis elegans

0 references

apoptotic process

0 references

1 reference

Cell division control protein 42 homolog CELE_R07G3.1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Lukas J Neukomm

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

Michael Otmar Hengartner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

author name string

S Zeng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

A P Frei

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

P A Huegli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

publication date

14 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

10 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

page(s)

845-853

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cdd.2014.23

10 March 2020

exact match

0 references

cites work

PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Cdc42 interacts with the exocyst complex to promote phagocytosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Cleaning up the mess: cell corpse clearance in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Integrin α PAT-2/CDC-42 signaling is required for muscle-mediated clearance of apoptotic cells in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Engulfment of apoptotic cells in C. elegans is mediated by integrin alpha/SRC signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Autoimmunity and the clearance of dead cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

CGEF-1 and CHIN-1 regulate CDC-42 activity during asymmetric division in the Caenorhabditis elegans embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Clearance of apoptotic corpses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

A protocol describing pharynx counts and a review of other assays of apoptotic cell death in the nematode worm Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreading

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Identification of a novel Cdc42 GEF that is localized to the PAT-3-mediated adhesive structure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

C-terminal SH3 domain of CrkII regulates the assembly and function of the DOCK180/ELMO Rac-GEF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Genome-wide RNAi screening in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

DIM-1, a novel immunoglobulin superfamily protein in Caenorhabditis elegans, is necessary for maintaining bodywall muscle integrity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

A blast from the past: clearance of apoptotic cells regulates immune responses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

C. elegans CED-12 acts in the conserved crkII/DOCK180/Rac pathway to control cell migration and cell corpse engulfment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Two C. elegans genes control the programmed deaths of specific cells in the pharynx

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4013519

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

CDC-42 and RHO-1 coordinate acto-myosin contractility and PAR protein localization during polarity establishment in C. elegans embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Phagocytosis promotes programmed cell death in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

Rac and roll over the corpses

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24632947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Correction: Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of phagocytosis by Rho GTPases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.23

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDD.2014.23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632947%20AND%20SRC:MED&resulttype=core&format=json