Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS. (Q33565842)

28 July 2017

Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS. (English)

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28 July 2017

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Luisa M Villar

1

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author name string

María C Sádaba

2

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28 July 2017

Ernesto Roldán

3

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28 July 2017

Jaime Masjuan

4

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28 July 2017

Pedro González-Porqué

5

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28 July 2017

Noelia Villarrubia

6

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28 July 2017

Mercedes Espiño

7

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28 July 2017

José A García-Trujillo

8

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28 July 2017

Alfredo Bootello

9

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28 July 2017

José C Alvarez-Cermeño

10

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28 July 2017

language of work or name

English

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publication date

1 January 2005

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Journal of Clinical Investigation

28 July 2017

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28 July 2017

115

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28 July 2017

1

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28 July 2017

187-194

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Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis.

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Origins and functions of B-1 cells with notes on the role of CD5

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Role of natural and immune IgM antibodies in immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Intrathecal antibody production against Chlamydia pneumoniae in multiple sclerosis is part of a polyspecific immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

B cells and antibodies in CNS demyelinating disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

The role of B cells and autoantibodies in multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Pathogenesis of tissue injury in MS lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

New diagnostic criteria for multiple sclerosis: guidelines for research protocols

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Lipid composition of the normal human brain: gray matter, white matter, and myelin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Temporal invariance and clonal uniformity of brain and cerebrospinal IgG, IgA, and IgM in multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Central nervous system myelin: structure, function, and pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

B cells expressing CD5 are increased in cerebrospinal fluid of patients with multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

CSF myelin basic protein, IgG and IgM levels in 101 MS patients before and after treatment with high-dose intravenous methylprednisolone.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Antibody-mediated CNS demyelination II. Focal spinal cord lesions induced by implantation of an IgM antisulfatide-secreting hybridoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Intrathecal IgM synthesis predicts the onset of new relapses and a worse disease course in MS.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

A sensitive and reproducible method for the detection of oligoclonal IgM bands

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539201

Antisulfatide antibodies in neuropathy: clinical and electrophysiologic correlates

31 October 2018

1 reference

12 December 2020

The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

1 reference

12 December 2020

Cutting edge commentary: two B-1 or not to be one

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12 December 2020

Antiganglioside antibodies in multifocal acquired sensory and motor neuropathy

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12 December 2020

Intrathecal IgM synthesis is a prognostic factor in multiple sclerosis

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12 December 2020

Intrathecal IgM synthesis in neurologic diseases: Relationship with disability in MS

1 reference

12 December 2020

An ultrasensitive method for the detection of oligoclonal IgG bands

1 reference

12 December 2020

Transition in CD45 isoform expression during differentiation of normal and abnormal B cells

1 reference

12 December 2020

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group

1 reference

12 December 2020

CD1b is expressed in multiple sclerosis lesions

1 reference

12 December 2020

Lymphocyte subsets in multiple sclerosis. A study with two-colour fluorescence analysis

1 reference

12 December 2020

MBP, anti-MBP and anti-PLP antibodies, and intrathecal complement activation in multiple sclerosis

1 reference

12 December 2020

Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI22833

1 reference

28 July 2017

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28 July 2017

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