Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry (Q33551708)

28 July 2017

Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry (English)

1 reference

Structure and dynamics of oligomeric intermediates in amyloid assembly

28 July 2017

1 reference

Gateway to Research

https://gtr.ukri.org/publication/overview?outcomeid=545a46ca768356.96683153&projectref=BB/H024875/1

26 April 2019

4

1 reference

28 July 2017

5

Alison E Ashcroft

0 references

Clare L Pashley

object named as

Clare L Pashley

series ordinal

2

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Charlotte A. Scarff

object named as

Charlotte A Scarff

series ordinal

3

0 references

Aneika C Leney

object named as

Aneika C Leney

series ordinal

1

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publication date

12 December 2013

1 reference

PubMed ID

24336936

full work available at URL

28 July 2017

http://eprints.whiterose.ac.uk/80192/

content deliverer

White Rose Research Online

object has role

published version

copyright license

Creative Commons Attribution 3.0 Unported

0 references

https://doi.org/10.1039/c3mb70420c

copyright license

Creative Commons Attribution 3.0 Unported

0 references

1 reference

28 July 2017

10

1 reference

28 July 2017

3

1 reference

28 July 2017

412-420

1 reference

PubMed ID

24336936

describes a project that uses

28 July 2017

1 reference

Insights into antiamyloidogenic properties of the green tea extract (-)-epigallocatechin-3-gallate toward metal-associated amyloid-β species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Novel insights into protein misfolding diseases revealed by ion mobility-mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Out-of-register -sheets suggest a pathway to toxic amyloid aggregates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Familial Alzheimer's disease mutations differentially alter amyloid β-protein oligomerization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

A recurrent D-strand association interface is observed in β-2 microglobulin oligomers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Structure and dynamics of oligomeric intermediates in β2-microglobulin self-assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

A diversity of assembly mechanisms of a generic amyloid fold

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Structural insights into the pre-amyloid tetramer of β-2-microglobulin from covalent labeling and mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

D-strand perturbation and amyloid propensity in beta-2 microglobulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

In vivo demonstration that alpha-synuclein oligomers are toxic

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Intermolecular alignment in β2-microglobulin amyloid fibrils

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

DE-loop mutations affect beta2 microglobulin stability, oligomerization, and the low-pH unfolded form

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Stacked sets of parallel, in-register beta-strands of beta2-microglobulin in amyloid fibrils revealed by site-directed spin labeling and chemical labeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Structure of the preamyloid dimer of beta-2-microglobulin from covalent labeling and mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Metal binding sheds light on mechanisms of amyloid assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

DE loop mutations affect beta2-microglobulin stability and amyloid aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Protein misfolding, functional amyloid, and human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Simulation of pH-dependent edge strand rearrangement in human beta-2 microglobulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

The aggregation kinetics of Alzheimer's beta-amyloid peptide is controlled by stochastic nucleation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Protein folding and misfolding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Crystal structure of monomeric human -2-microglobulin reveals clues to its amyloidogenic properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

The solution structure of human β2-microglobulin reveals the prodromes of its amyloid transition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Characterization of the interactions between MHC class I subunits: a systematic approach for the engineering of higher affinity variants of beta 2-microglobulin.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

Molecular chaperones in cellular protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

1H NMR assignments and secondary structure of human beta 2-microglobulin in solution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006425

A generic mechanism of beta2-microglobulin amyloid assembly at neutral pH involving a specific proline switch.

21 June 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Mass spectrometry and the amyloid problem--how far can we go in the gas phase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic protein beta(2)-microglobulin upon release from the MHC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Competition between intramolecular and intermolecular interactions in an amyloid-forming protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Amyloid fibril formation in the context of full-length protein: effects of proline mutations on the amyloid fibril formation of beta2-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3MB70420C

A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24336936

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1039/C3MB70420C

1 reference

Dimensions Publication ID

28 July 2017

0 references

1049708346

0 references

Microsoft Academic ID

0 references

1 reference

28 July 2017

1 reference

PubMed ID

24336936