HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons (Q33526300)

27 July 2017

HH domain of Alzheimer's disease Abeta provides structural basis for neuronal binding in PC12 and mouse cortical/hippocampal neurons (English)

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27 July 2017

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Joseph F Poduslo

1

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27 July 2017

Emily J Gilles

2

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27 July 2017

Muthu Ramakrishnan

3

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27 July 2017

Kyle G Howell

4

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27 July 2017

Thomas M Wengenack

5

1 reference

27 July 2017

Geoffry L Curran

6

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27 July 2017

Karunya K Kandimalla

7

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27 July 2017

language of work or name

English

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publication date

21 January 2010

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27 July 2017

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27 July 2017

5

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27 July 2017

1

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27 July 2017

e8813

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Creative Commons Attribution 4.0 International

27 July 2017

start time

21 January 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Serine racemase is predominantly localized in neurons in mouse brain

21 June 2018

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Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease

21 June 2018

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Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

21 June 2018

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Fitting neurological protein aggregation kinetic data via a 2-step, minimal/"Ockham's razor" model: the Finke-Watzky mechanism of nucleation followed by autocatalytic surface growth

21 June 2018

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Intracellular amyloid-beta in Alzheimer's disease

21 June 2018

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Histidines 13 and 14 in the Abeta sequence are targets for inhibition of Alzheimer's disease Abeta ion channel and cytotoxicity.

21 June 2018

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High sensitivity analysis of amyloid-beta peptide composition in amyloid deposits from human and PS2APP mouse brain

21 June 2018

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Mechanism of thioflavin T binding to amyloid fibrils.

21 June 2018

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Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

21 June 2018

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Amyloid beta-peptide: the inside story

21 June 2018

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A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

21 June 2018

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Design and chemical synthesis of a magnetic resonance contrast agent with enhanced in vitro binding, high blood-brain barrier permeability, and in vivo targeting to Alzheimer's disease amyloid plaques.

21 June 2018

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The genetics of adult-onset neuropsychiatric disease: complexities and conundra?

21 June 2018

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Intracellular A-beta amyloid, a sign for worse things to come?

21 June 2018

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Intracellular accumulation of beta-amyloid(1-42) in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease.

21 June 2018

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Clearing the brain's amyloid cobwebs

21 June 2018

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Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

21 June 2018

1 reference

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Intraneuronal Abeta42 accumulation in human brain.

21 June 2018

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Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease.

21 June 2018

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Competition of Abeta amyloid peptide and apolipoprotein E for receptor-mediated endocytosis.

21 June 2018

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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

21 June 2018

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Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

21 June 2018

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Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system

21 June 2018

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Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 June 2018

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Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact

21 June 2018

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Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.

21 June 2018

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Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein

21 June 2018

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Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.

21 June 2018

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Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

31 October 2018

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The cell-selective neurotoxicity of the Alzheimer's Abeta peptide is determined by surface phosphatidylserine and cytosolic ATP levels. Membrane binding is required for Abeta toxicity.

31 October 2018

1 reference

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Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

31 October 2018

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Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity

31 October 2018

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Effect of forskolin on synaptotagmin IV protein trafficking in PC12 cells.

31 October 2018

1 reference

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Determination of diffusion and partition coefficients of propofol in rat brain tissue: implications for studies of drug action in vitro.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

The HHQK domain of beta-amyloid provides a structural basis for the immunopathology of Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809098

The brain slice preparation: a tribute to the pioneer Henry McIlwain

31 October 2018

1 reference

12 December 2020

Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease

1 reference

12 December 2020

Interaction of human and mouse Abeta peptides

1 reference

12 December 2020

Targeting alzheimer amyloid plaques in vivo

1 reference

12 December 2020

Examining the zinc binding site of the amyloid-beta peptide

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0008813

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DOI

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27 July 2017

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27 July 2017

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