COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. (Q33508581)

27 July 2017

COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. (English)

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27 July 2017

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6

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27 July 2017

4

Elsken van der Wall

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27 July 2017

5

Paul J van Diest

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27 July 2017

Bart van de Sluis

1

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27 July 2017

Arjan J Groot

2

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27 July 2017

Jeroen Vermeulen

3

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27 July 2017

Leo W Klomp

7

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27 July 2017

Marc Vooijs

8

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27 July 2017

language of work or name

English

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publication date

5 October 2009

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27 July 2017

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27 July 2017

4

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27 July 2017

10

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27 July 2017

e7332

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Creative Commons Attribution 4.0 International

27 July 2017

start time

5 October 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice

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RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha

21 June 2018

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COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

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Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha

21 June 2018

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PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

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The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein

21 June 2018

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Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 June 2018

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21 June 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 June 2018

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Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

21 June 2018

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 June 2018

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21 June 2018

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Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene

21 June 2018

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COMMD1: a novel protein involved in the proteolysis of proteins.

21 June 2018

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

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Nuclear-cytosolic transport of COMMD1 regulates NF-kappaB and HIF-1 activity

21 January 2018

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Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells

31 October 2018

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Constitutive/hypoxic degradation of HIF-alpha proteins by the proteasome is independent of von Hippel Lindau protein ubiquitylation and the transactivation activity of the protein

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19802386

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0007332

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release_lpfoycghqjaablkknuccikphoy

27 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lpfoycghqjaablkknuccikphoy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

2750754

1 reference

27 July 2017

1 reference