Production of a recombinant mouse monoclonal antibody in transgenic silkworm cocoons (Q33501332)

27 July 2017

title

Production of a recombinant mouse monoclonal antibody in transgenic silkworm cocoons (English)

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27 July 2017

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Masashi Iizuka

1

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27 July 2017

Shingo Ogawa

2

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27 July 2017

Atsushi Takeuchi

3

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27 July 2017

Shinichi Nakakita

4

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27 July 2017

Yuhki Kubo

5

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27 July 2017

Yoshitaka Miyawaki

6

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27 July 2017

Jun Hirabayashi

7

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27 July 2017

Masahiro Tomita

8

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27 July 2017

language of work or name

English

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publication date

9 September 2009

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27 July 2017

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27 July 2017

volume

276

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27 July 2017

issue

20

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27 July 2017

page(s)

5806-5820

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Therapeutic antibody expression technology

27 July 2017

cites work

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An antibody produced in tobacco expressing a hybrid beta-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes

21 January 2018

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Galactose-extended glycans of antibodies produced by transgenic plants

21 January 2018

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Glycan optimization of a human monoclonal antibody in the aquatic plant Lemna minor

21 January 2018

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Characterization of humanized antibodies secreted by Aspergillus niger

21 January 2018

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Production of human monoclonal antibody in eggs of chimeric chickens.

21 January 2018

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Efficient expression of recombinant human monoclonal antibodies in Drosophila S2 cells

21 January 2018

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Effects of co-expressing chaperone BiP on functional antibody production in the baculovirus system

21 January 2018

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Differential N-glycan patterns of secreted and intracellular IgG produced in Trichoplusia ni cells

21 January 2018

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Specificity of IgG and IgE antibodies against plant and insect glycoprotein glycans determined with artificial glycoforms of human transferrin

21 January 2018

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Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.

21 January 2018

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In vivo trafficking and catabolism of IgG1 antibodies with Fc associated carbohydrates of differing structure

21 January 2018

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In vivo glyco-engineered antibody with improved lytic potential produced by an innovative non-mammalian expression system.

21 January 2018

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Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

21 January 2018

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Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6:6:1 molar ratio

21 January 2018

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Developmental switches of sericin mRNA splicing in individual cells of Bombyx mori silkgland

21 January 2018

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Cloning and characterization of the highly polymorphic Ser2 gene of Bombyx mori

21 January 2018

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Structure and organization of the Bombyx mori sericin 1 gene and of the sericins 1 deduced from the sequence of the Ser 1B cDNA.

21 January 2018

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Isolation of three main sericin components from the cocoon of the silkworm, Bombyx mori

21 January 2018

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Germline transformation of the silkworm Bombyx mori L. using a piggyBac transposon-derived vector.

21 January 2018

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Transgenic silkworms produce recombinant human type III procollagen in cocoons

21 January 2018

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The generation of germline transgenic silkworms for the production of biologically active recombinant fusion proteins of fibroin and human basic fibroblast growth factor

21 January 2018

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Generation of hybrid transgenic silkworms that express Bombyx mori prolyl-hydroxylase alpha-subunits and human collagens in posterior silk glands: Production of cocoons that contained collagens with hydroxylated proline residues

21 January 2018

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Generation of a transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon: production of recombinant human serum albumin

21 January 2018

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A germline transgenic silkworm that secretes recombinant proteins in the sericin layer of cocoon

21 January 2018

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Translational enhancement of recombinant protein synthesis in transgenic silkworms by a 5'-untranslated region of polyhedrin gene of Bombyx mori Nucleopolyhedrovirus

21 January 2018

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Biological significance of carbohydrate chains on monoclonal antibodies

21 January 2018

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Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines

21 January 2018

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Crystal structure of fungal lectin: six-bladed beta-propeller fold and novel fucose recognition mode for Aleuria aurantia lectin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Structures of the N-linked oligosaccharides of the membrane glycoproteins from three lepidopteran cell lines (Sf-21, IZD-Mb-0503, Bm-N).

21 January 2018

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Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

cDNA cloning of the immunoglobulin heavy chain binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Heavy chain dimers as well as complete antibodies are efficiently formed and secreted from Drosophila via a BiP-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Studies on middle and posterior silk glands of silkworm (Bombyx mori) using two-dimensional electrophoresis and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

N-Linked glycosylation of a baculovirus-expressed recombinant glycoprotein in insect larvae and tissue culture cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Insect cells contain an unusual, membrane-bound beta-N-acetylglucosaminidase probably involved in the processing of protein N-glycans.

21 January 2018

1 reference

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Processing of asparagine-linked oligosaccharides in insect cells. N-acetylglucosaminyltransferase I and II activities in cultured lepidopteran cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Evidence for alternative splicing and developmental regulation of the Drosophila melanogaster Mgat2 (N-acetylglucosaminyltransferase II) gene

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Glycosylation in lepidopteran insect cells: identification of a beta 1-->4-N-acetylgalactosaminyltransferase involved in the synthesis of complex-type oligosaccharide chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Stable expression of mammalian beta 1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Engineering lepidopteran insect cells for sialoglycoprotein production by genetic transformation with mammalian beta 1,4-galactosyltransferase and alpha 2,6-sialyltransferase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Distinct N-glycan fucosylation potentials of three lepidopteran cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Identification of core alpha 1,3-fucosylated glycans and cloning of the requisite fucosyltransferase cDNA from Drosophila melanogaster. Potential basis of the neural anti-horseadish peroxidase epitope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Fucosyltransferase substrate specificity and the order of fucosylation in invertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Alteration of brain type N-glycans in neurological mutant mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Method for purification of fluorescence-labeled oligosaccharides by pyridylamination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

Capillary electrophoresis with laser-induced fluorescence detection for detailed studies on N-linked oligosaccharide profile of therapeutic recombinant monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2009.07262.X

10.1111/J.1742-4658.2009.07262.X

21 January 2018

Identifiers

DOI

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27 July 2017

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