The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes (Q33500402)

27 July 2017

The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes (English)

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27 July 2017

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GOA release 2020-03-11

Prosaposin

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GOA release 2020-03-11

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Jibin Zeng

1

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27 July 2017

Jesse Racicott

series ordinal

2

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27 July 2017

Carlos R Morales

series ordinal

3

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27 July 2017

language of work or name

English

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publication date

2 September 2009

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Experimental Cell Research

27 July 2017

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27 July 2017

315

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27 July 2017

3112-3124

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27 July 2017

18

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Towards a human repertoire of monocytic lysosomal proteins

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The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin

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The trafficking of prosaposin (SGP-1) and GM2AP to the lysosomes of TM4 Sertoli cells is mediated by sortilin and monomeric adaptor proteins

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1 reference

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The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

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AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes

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The lysosomal trafficking of acid sphingomyelinase is mediated by sortilin and mannose 6-phosphate receptor

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Sortilin mediates the lysosomal targeting of cathepsins D and H

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Hormonal regulation of sulfated glycoprotein-1 synthesis by nonciliated cells of the efferent ducts of adult rats

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Role of sulfated glycoprotein-1 (SGP-1) in the disposal of residual bodies by Sertoli cells of the rat.

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Role of sialic acid in the endocytosis of prosaposin by the nonciliated cells of the rat efferent ducts

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Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

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Identification of a novel sequence involved in lysosomal sorting of the sphingolipid activator protein prosaposin

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Sulfated glycoprotein-2 synthesized by nonciliated cells of the efferent ducts is targeted to the lysosomal compartment

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Study of the mouse sortilin gene: Effects of its transient silencing by RNA interference in TM4 Sertoli cells

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Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids.

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Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury.

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Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase

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Functional organization of the sortilin Vps10p domain

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Mannose 6-phosphate receptor-mediated endocytosis of acid hydrolases: internalization of beta-glucuronidase is accompanied by a limited dephosphorylation

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Different motifs regulate trafficking of SorCS1 isoforms.

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Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval

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Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.

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Identifiers

DOI

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27 July 2017

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