Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth (Q33405383)

26 July 2017

Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth (English)

1 reference

26 July 2017

1 reference

John A Beutler

6

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author name string

Iwona E Wrona

1

1 reference

26 July 2017

Jason T Lowe

2

1 reference

26 July 2017

Thomas J Turbyville

3

1 reference

26 July 2017

Tanya R Johnson

4

1 reference

26 July 2017

Julien Beignet

5

1 reference

26 July 2017

James S Panek

7

1 reference

26 July 2017

language of work or name

English

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publication date

1 March 2009

1 reference

Journal of Organic Chemistry

26 July 2017

1 reference

26 July 2017

74

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26 July 2017

5

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26 July 2017

1897-1916

1 reference

Total synthesis of (-)-kendomycin

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

The dual mode of action of bistramide A entails severing of filamentous actin and covalent protein modification

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis and stereochemical reassignment of (+)-neopeltolide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis of herboxidiene/GEX 1A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

The structural determinants of macrolide-actin binding: in silico insights.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis of bistramide A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

[4 + 2]-annulations of chiral organosilanes: Application to the total synthesis of leucascandrolide A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Actin-targeting natural products: structures, properties and mechanisms of action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis of a 28-member stereoisomer library of murisolins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

A convenient multigram synthesis of highly enantioenriched methyl 3-silylglycidates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Enantioselective total synthesis of bistramide A

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Actin is the primary cellular receptor of bistramide A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis of (-)-apicularen A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Fluorous mixture synthesis of stereoisomer libraries: total syntheses of (+)-murisolin and fifteen diastereoisomers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Trisoxazole macrolide toxins mimic the binding of actin-capping proteins to actin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

A mild, chemoselective protocol for the removal of thioketals and thioacetals mediated by Dess-Martin periodinane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Small-molecule inhibitors of actin dynamics and cell motility.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Actin-binding marine macrolides: total synthesis and biological importance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Total synthesis of a stereoisomer of bistramide C and assignment of configuration of the natural product

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

The NCI anti-cancer drug screen: a smart screen to identify effectors of novel targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Effects of cytochalasin and phalloidin on actin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Structure basis for antitumor effect of aplyronine a.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Synthesis of all 16 stereoisomers of pinesaw fly sex pheromones--tools and tactics for solving problems in fluorous mixture synthesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Synthesis of bistramide A.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

A new synthesis and stereocontrolled functionalization of substituted silacyclopent-3-enes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Spectroscopic study on charge transfer molecular complexes of pyrazole derivatives with some pi-electron acceptors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3480235

Bistratene A Induces a Microtubule-Dependent Block in Cytokinesis and Altered Stathmin Expression in HL60 Cells

31 October 2018

1 reference

12 December 2020

New anti-actin drugs in the study of the organization and function of the actin cytoskeleton

1 reference

12 December 2020

Analysis of some antifungal drugs by spectrophotometric and spectrofluorimetric methods in different pharmaceutical dosage forms

1 reference

12 December 2020

Total Synthesis of Siphonarin B and Dihydrosiphonarin B

1 reference

12 December 2020

Stereochemical Control in Organic Synthesis Using Silicon-Containing Compounds

1 reference

12 December 2020

SiMe3-based homologation-epoxidation-cyclization strategy for ladder THP synthesis

1 reference

12 December 2020

Blockade of sodium channels by bistramide A in voltage-clamped frog skeletal muscle fibres

1 reference

12 December 2020

Total synthesis of callipeltoside A

1 reference

12 December 2020

Highly efficient two-step synthesis of C-sp3-centered geminal diiodides

1 reference

12 December 2020

Structural basis of swinholide A binding to actin

1 reference

12 December 2020

Total synthesis and structure validation of (+)-bistramide C

1 reference

12 December 2020

Synthesis and [4 + 2]-annulation of enantioenriched (z)-crotylsilanes: preparation of the C1-C13 fragment of bistramide A

1 reference

12 December 2020

Systematic Assignment of the Configuration of Flexible Natural Products by Spectroscopic and Computational Methods: The Bistramide C Analysis

1 reference

12 December 2020

Structure of bistramide A-actin complex at a 1.35 angstroms resolution

1 reference

12 December 2020

Synthesis of derivatives of potent antitumor bistramides D and A leading to the first crystal structure of natural bistramide D

1 reference

12 December 2020

Spirodionic acid, a novel metabolite from Streptomyces sp., part 2: total synthesis through a twofold michael addition as a selective spiroannelation strategy.

1 reference

12 December 2020

Stereoselective total synthesis of bistramide A

1 reference

12 December 2020

Small peptide inhibitors of smooth muscle myosin light chain kinase

1 reference

12 December 2020

Novel cytotoxic compounds from the ascidian Lissoclinum bistratum

1 reference

12 December 2020

Reduction of Carbonyl Compounds with Chiral Oxazaborolidine Catalysts: A New Paradigm for Enantioselective Catalysis and a Powerful New Synthetic Method

1 reference

12 December 2020

Bistramide A, a new toxin from the urochordata Lissoclinum bistratum Sluiter: isolation and preliminary characterization

1 reference

12 December 2020

Bistramides A, B, C, D, and K: a new class of bioactive cyclic polyethers from Lissoclinum bistratum

1 reference

12 December 2020

Alteration of the voltage-dependence of the twitch tension in frog skeletal muscle fibres by a polyether, Bistramide A

1 reference

12 December 2020

The polyether Bistramide A affects the calcium sensitivity of the contractile proteins in frog atrial heart muscle

1 reference

12 December 2020

Bistramide A-induced irreversible arrest of cell proliferation in a non-small-cell bronchopulmonary carcinoma is similar to induction of terminal maturation

1 reference

12 December 2020

The Polyether Bistratene A Activates Protein Kinase C–δ and Induces Growth Arrest in HL60 Cells

1 reference

12 December 2020

Novel actin depolymerizing macrolide aplyronine A

1 reference

12 December 2020

Identifiers

DOI

10.1021/JO802269Q

1 reference

26 July 2017

1 reference

26 July 2017

1 reference