A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation (Q33398520)

26 July 2017

title

A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation (English)

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26 July 2017

Randolph B Caldwell

5

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author name string

Artem Blagodatski

1

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26 July 2017

Vera Batrak

2

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26 July 2017

Sabine Schmidl

3

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26 July 2017

Ulrike Schoetz

4

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26 July 2017

Hiroshi Arakawa

6

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26 July 2017

Jean-Marie Buerstedde

7

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26 July 2017

publication date

9 January 2009

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26 July 2017

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26 July 2017

volume

5

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26 July 2017

issue

1

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26 July 2017

page(s)

e1000332

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

9 January 2009

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Cutting edge: a cis-acting DNA element targets AID-mediated sequence diversification to the chicken Ig light chain gene locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Protein evolution by hypermutation and selection in the B cell line DT40

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Targeting of somatic hypermutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

RDM1, a novel RNA recognition motif (RRM)-containing protein involved in the cell response to cisplatin in vertebrates.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Activation-induced cytidine deaminase initiates immunoglobulin gene conversion and hypermutation by a common intermediate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Genome-wide somatic hypermutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

AID is essential for immunoglobulin V gene conversion in a cultured B cell line

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Mutant loxP vectors for selectable marker recycle and conditional knock-outs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Reevaluation of 3'Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

A lambda 3' enhancer drives active and untemplated somatic hypermutation of a lambda 1 transgene.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Somatic hypermutation of a lambda 2 transgene under the control of the lambda enhancer or the heavy chain intron enhancer.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

The chicken immunoglobulin λ light chain gene is transcriptionally controlled by a modularly organized enhancer and an octamer-dependent silencer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Increased ratio of targeted to random integration after transfection of chicken B cell lines.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2607555

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000332

Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000332

Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000332

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000332

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

21 January 2018

1 reference

12 December 2020

Multiple sequences from downstream of the J kappa cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain

1 reference

12 December 2020

The influence of transcriptional orientation on endogenous switch region function

1 reference

12 December 2020

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1000332

Identifiers

DOI

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26 July 2017

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26 July 2017

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