Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation (Q33394424)

26 July 2017

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation (English)

1 reference

26 July 2017

dasatinib monohydrate

1 reference

1 reference

Alexandra Mazharian

1

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Steve P. Watson

object named as

Steve P Watson

series ordinal

5

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Cedric Ghevaert

object named as

Cedric Ghevaert

series ordinal

2

0 references

Steffen Massberg

series ordinal

4

object named as

Steffen Massberg

1 reference

26 July 2017

Lin Zhang

3

1 reference

PubMed ID

21385851

26 July 2017

language of work or name

English

0 references

publication date

8 March 2011

1 reference

26 July 2017

1 reference

26 July 2017

117

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26 July 2017

19

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26 July 2017

5198-5206

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PubMed ID

21385851

describes a project that uses

26 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3109542/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure

21 June 2018

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The new tyrosine-kinase inhibitor and anticancer drug dasatinib reversibly affects platelet activation in vitro and in vivo.

21 June 2018

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21 June 2018

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CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation

21 June 2018

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A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice

21 June 2018

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21 June 2018

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Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

21 June 2018

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A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

21 June 2018

1 reference

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The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants

21 June 2018

1 reference

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The biogenesis of platelets from megakaryocyte proplatelets

21 June 2018

1 reference

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The molecular mechanisms that control thrombopoiesis

21 June 2018

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Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656.

21 June 2018

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Overriding imatinib resistance with a novel ABL kinase inhibitor

21 June 2018

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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

21 June 2018

1 reference

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The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production

21 June 2018

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Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

21 June 2018

1 reference

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Megakaryocytic differentiation is accompanied by a reduction in cell migratory potential.

21 June 2018

1 reference

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Identification of critical antigen-specific mechanisms in the development of immune thrombocytopenic purpura in mice.

21 June 2018

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BCR-ABL tyrosine kinase activity regulates the expression of multiple genes implicated in the pathogenesis of chronic myeloid leukemia.

21 June 2018

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Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies

21 June 2018

1 reference

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Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation

21 June 2018

1 reference

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Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1.

21 June 2018

1 reference

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Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes

21 June 2018

1 reference

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Molecular consequences of the BCR-ABL translocation in chronic myelogenous leukemia

21 June 2018

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Src family kinases are essential for primary aggregation by G(i) -coupled receptors

21 June 2018

1 reference

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Differentiation of murine committed megakaryocytic progenitors isolated by a novel strategy reveals the complexity of GATA and Ets factor involvement in megakaryocytopoiesis and an unexpected potential role for GATA-6.

31 October 2018

1 reference

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Increased megakaryocytopoiesis in Lyn-deficient mice

31 October 2018

1 reference

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Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109542

Identification and activation of Src family kinases in primary megakaryocytes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109542

Identification of the Src family kinases, Lck and Fgr in platelets. Their tyrosine phosphorylation status and subcellular distribution compared with other Src family members

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21385851

12 December 2020

inferred from PubMed ID database lookup

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21385851

12 December 2020

inferred from PubMed ID database lookup

In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21385851

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2010-12-326850

1 reference

26 July 2017

1 reference

26 July 2017

1 reference

PubMed ID

21385851