Exceptional amyloid beta peptide hydrolyzing activity of nonphysiological immunoglobulin variable domain scaffolds (Q33381465)

26 July 2017

Exceptional amyloid beta peptide hydrolyzing activity of nonphysiological immunoglobulin variable domain scaffolds (English)

1 reference

26 July 2017

Stephane Boivin

4

0 references

author name string

Hiroaki Taguchi

1

1 reference

26 July 2017

Stephanie Planque

2

1 reference

26 July 2017

Gopal Sapparapu

3

1 reference

26 July 2017

Mariko Hara

5

1 reference

26 July 2017

Yasuhiro Nishiyama

6

1 reference

26 July 2017

Sudhir Paul

7

1 reference

26 July 2017

language of work or name

English

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publication date

30 October 2008

1 reference

Journal of Biological Chemistry

26 July 2017

1 reference

26 July 2017

283

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26 July 2017

52

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26 July 2017

36724-36733

1 reference

Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Autoantibody-catalyzed hydrolysis of amyloid beta peptide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Antibodies to the superantigenic site of HIV-1 gp120: hydrolytic and binding activities of the light chain subunit

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Monomeric Fc fusions: impact on pharmacokinetic and biological activity of protein therapeutics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Crystal structure of a glycosylated Fab from an IgM cryoglobulin with properties of a natural proteolytic antibody

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Catalytic antibodies and their applications

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Antibody repertoire development in cartilaginous fish

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Antibody repertoire development in camelids

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Computational prediction of native protein ligand-binding and enzyme active site sequences

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Broadly distributed nucleophilic reactivity of proteins coordinated with specific ligand binding activity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Intravenous immunoglobulins containing antibodies against beta-amyloid for the treatment of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Current progress in beta-amyloid immunotherapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Proteolytic antibody light chains alter beta-amyloid aggregation and prevent cytotoxicity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Immunotherapy as a therapeutic treatment for neurodegenerative disorders.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Irreversible inhibitors of serine, cysteine, and threonine proteases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Expression of single-chain Fv-Fc fusions in Pichia pastoris

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Human and murine immunoglobulin expression vector cassettes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

A helper phage to improve single-chain antibody presentation in phage display

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Binding of nascent collagen by amyloidogenic light chains and amyloid fibrillogenesis in monolayers of human fibrocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Structural basis for amide hydrolysis catalyzed by the 43C9 antibody

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Catalytic triads and their relatives

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Amyloid in Alzheimer's disease and prion-related encephalopathies: studies with synthetic peptides

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

The binding of opioid peptides to the Mcg light chain dimer: flexible keys and adjustable locks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Antibody-antigen complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Novel vectors for the expression of antibody molecules using variable regions generated by polymerase chain reaction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

DNA hydrolyzing autoantibodies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

The organization, expression, and evolution of antibody genes and other multigene families

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

A steroid immunoassay based on antibody-enhanced hydrolysis of a steroid-umbelliferone conjugate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2606003

Catalytic activity of antibodies against factor VIII in patients with hemophilia A.

14 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Immunization of rabbits with DNase I produces polyclonal antibodies with DNase and RNase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Phosphonate ester probes for proteolytic antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Ontogeny of proteolytic immunity: IgM serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Covalent reactivity of phosphonate monophenyl esters with serine proteinases: an overlooked feature of presumed transition state analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

A rapid and efficient PCR-based mutagenesis method applicable to cell physiology study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Abeta oligomer-mediated long-term potentiation impairment involves protein phosphatase 1-dependent mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Hydrolysis of the amyloid beta-peptide (A beta) 1-40 between Asp23-Val24 produces non-aggregating fragments. An electrospray mass spectrometric study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Modeling Alzheimer's disease immune therapy mechanisms: interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Vessel ultrastructure in APP23 transgenic mice after passive anti-Abeta immunotherapy and subsequent intracerebral hemorrhage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806766200

Targeted destruction of the HIV-1 coat protein gp41 by a catalytic antibody light chain

21 January 2018

1 reference

12 December 2020

Catalysis and regulation - from structure to function

1 reference

12 December 2020

Gross conformation of free polypeptide chains from rabbit immunoglobulin G. II. Light chain

1 reference

12 December 2020

Catalytic hydrolysis of vasoactive intestinal peptide by human autoantibody

1 reference

12 December 2020

Irreversible inhibition of a monoclonal antibody by a nitrophenyl ester

1 reference

12 December 2020

Vasoactive intestinal peptide hydrolysis by antibody light chains

1 reference

12 December 2020

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

1 reference

12 December 2020

Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases

1 reference

12 December 2020

Neutral endopeptidase can hydrolyze beta-amyloid(1-40) but shows no effect on beta-amyloid precursor protein metabolism

1 reference

12 December 2020

Site-directed mutagenesis of proteolytic antibody light chain

1 reference

12 December 2020

Cleavage specificity of a proteolytic antibody light chain and effects of the heavy chain variable domain

1 reference

12 December 2020

DNA-hydrolyzing activity of the light chain of IgG antibodies from milk of healthy human mothers

1 reference

12 December 2020

Mechanisms of A beta plaque clearance following passive A beta immunization

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M806766200

1 reference

26 July 2017

1 reference

26 July 2017

1 reference