A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia (Q33372611)

26 July 2017

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia (English)

1 reference

26 July 2017

1 reference

Marina R Carpinelli

6

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Sarah Ellis

Sarah Ellis

5

0 references

Nicos A. Nicola

Nicos A Nicola

10

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Doug Hilton

Douglas J Hilton

11

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Ian J Majewski

Ian J Majewski

1

0 references

Lisa A Mielke

Lisa A Mielke

3

0 references

Donald Metcalf

2

Donald Metcalf

1 reference

26 July 2017

8

Ladina Di Rago

1 reference

26 July 2017

4

Danielle L Krebs

1 reference

26 July 2017

9

Jason Corbin

1 reference

26 July 2017

7

Sandra Mifsud

1 reference

26 July 2017

Warren S Alexander

12

1 reference

PubMed ID

16966598

26 July 2017

language of work or name

English

0 references

publication date

11 September 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

1 reference

26 July 2017

103

1 reference

26 July 2017

14146-14151

1 reference

26 July 2017

38

1 reference

Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Origins of leukaemia in children with Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Effects of the R216Q mutation of GATA-1 on erythropoiesis and megakaryocytopoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

X-linked thrombocytopenia caused by a novel mutation of GATA-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Consequences of GATA-1 deficiency in megakaryocytes and platelets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Forced GATA-1 expression in the murine myeloid cell line M1: induction of c-Mpl expression and megakaryocytic/erythroid differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Alternative translation initiation site usage results in two functionally distinct forms of the GATA-1 transcription factor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599926

Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0606439103

Comprehensive analysis of gene alterations in acute megakaryoblastic leukemia of Down's syndrome.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0606439103

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0606439103

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16966598

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0606439103

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference

PubMed ID

16966598