Pharmacokinetic and pharmacodynamic effects of high-dose monoclonal antibody therapy in a rat model of immune thrombocytopenia (Q33370766)

26 July 2017

title

Pharmacokinetic and pharmacodynamic effects of high-dose monoclonal antibody therapy in a rat model of immune thrombocytopenia (English)

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26 July 2017

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Feng Jin

1

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26 July 2017

Zia R Tayab

series ordinal

2

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26 July 2017

Joseph P Balthasar

series ordinal

3

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26 July 2017

language of work or name

English

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publication date

1 January 2005

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26 July 2017

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26 July 2017

volume

7

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26 July 2017

issue

4

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26 July 2017

page(s)

E895-902

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Antibody pharmacokinetics and pharmacodynamics

26 July 2017

cites work

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Pharmacokinetic/pharmacodynamic modeling of the effects of intravenous immunoglobulin on the disposition of antiplatelet antibodies in a rat model of immune thrombocytopenia

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Pharmacokinetics, pharmacodynamics, and platelet binding of an anti-glycoprotein IIb/IIIa monoclonal antibody (7E3) in the rat: a quantitative rat model of immune thrombocytopenic purpura

21 June 2018

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21 June 2018

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Platelet-associated antibody to glycoprotein IIb/IIIa from chronic immune thrombocytopenic purpura patients often binds to divalent cation-dependent antigens

21 June 2018

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21 June 2018

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Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high-dose intravenous gamma globulin

21 June 2018

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21 June 2018

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21 June 2018

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12 December 2020

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12 December 2020

Increased clearance of IgG in mice that lack beta 2-microglobulin: possible protective role of FcRn

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Shortage of intravenous immunoglobulin

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A Theoretical Model of γ-Globulin Catabolism

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Development and validation of enzyme-linked immunosorbent assays for quantification of anti-methotrexate IgG and Fab in mouse and rat plasma

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Application of pharmacokinetic-pharmacodynamic modeling to predict the kinetic and dynamic effects of anti-methotrexate antibodies in mice

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12 December 2020

Identifiers

DOI

10.1208/AAPSJ070487

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Dimensions Publication ID

26 July 2017

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26 July 2017

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