Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index (Q33364177)

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English	Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index	scientific article

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scholarly article

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Europe PubMed Central

26 July 2017

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Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index (English)

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Europe PubMed Central

26 July 2017

Christian Gieger

4

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26 July 2017

Christa Meisinger

12

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Barbara Thorand

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Barbara Thorand

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2

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Thomas Illig

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Jaakko Tuomilehto

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Jaakko Tuomilehto

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Harald Grallert

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Harald Grallert

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Heiner Boeing

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Cornelia Huth

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Joan Vendrell

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Florian Kronenberg

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Florian Kronenberg

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Stephen E Humphries

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Steve E Humphries

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Oluf Borbye Pedersen

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Oluf Pedersen

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Michael Boehnke

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Michael Boehnke

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26 July 2017

Heather M Stringham

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Heather M Stringham

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John-Olov Jansson

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John-Olov Jansson

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Valeriya Lyssenko

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Valeriya Lyssenko

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Leif Groop

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Matthias Möhlig

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Matthias Mohlig

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14

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Norman Klopp

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Heinz Erich Wichmann

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H-Erich Wichmann

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Wolfgang Lieb

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36

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Iris M Heid

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Caren Vollmert

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Yasmin H Hamid

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Wolfgang Rathmann

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Wolfgang Rathmann

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31

object named as

Luis Gallart

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15

object named as

Henning Gohlke

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Christian Hengstenberg

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object named as

Christian Hengstenberg

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author name string

Christian Herder

3

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26 July 2017

Torben Hansen

10

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Angela Doring

13

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Helen Ireland

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26 July 2017

Jeffrey W Stephens

21

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26 July 2017

Ingrid Wernstedt Asterholm

22

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26 July 2017

Jose-Manuel Fernandez-Real

29

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Abel Lopez-Bermejo

30

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publication date

1 January 2009

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26 July 2017

Annals of Medicine

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41

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2

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128-138

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26 July 2017

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

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21 June 2018

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

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The Genetic Basis of Type 2 Diabetes.

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21 June 2018

Interleukin-6 and diabetes: the good, the bad, or the indifferent?

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21 June 2018

Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness.

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21 June 2018

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

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21 June 2018

Interleukin-6 serum levels and genotypes influence the risk for myocardial infarction

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21 June 2018

Interleukin-6 promoter haplotypes and interleukin-6 cytokine responses

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21 June 2018

Multiple levels of regulation of the interleukin-6 system in stroke

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21 June 2018

Interleukin-6 stimulates lipolysis and fat oxidation in humans

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21 June 2018

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

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Quantifying heterogeneity in a meta-analysis

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21 June 2018

Muscle-derived interleukin-6: possible biological effects

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21 June 2018

Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery

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21 June 2018

Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation

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21 June 2018

Meta-analysis: formulating, evaluating, combining, and reporting

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21 June 2018

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

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21 June 2018

Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects.

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21 January 2018

Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?

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21 January 2018

Interleukin-6 gene polymorphism and insulin sensitivity.

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

The interleukin 6-174G/C polymorphism is associated with indices of obesity in men.

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Interleukin-6 g.−174G>C Promoter Polymorphism Is Associated with Obesity in the EPIC-Potsdam Study*

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21 January 2018

A common interleukin-6 gene promoter polymorphism influences the clinical characteristics of women with polycystic ovary syndrome

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4.

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Genetic variation in IL6 gene and type 2 diabetes: tagging-SNP haplotype analysis in large-scale case-control study and meta-analysis

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

A method for meta-analysis of molecular association studies

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21 January 2018

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Interleukin-6-deficient mice develop mature-onset obesity

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Metabolic effects of interleukin-6 in human splanchnic and adipose tissue

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21 January 2018

Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors

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21 January 2018

Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individuals

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21 January 2018

BMI modifies associations of IL-6 genotypes with insulin resistance: the Framingham Study.

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21 January 2018

Polymorphisms in the interleukin 6 and transforming growth factor beta1 gene and risk of dementia. The Rotterdam Study.

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21 January 2018

Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Bias in meta-analysis detected by a simple, graphical test

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Body mass index and C-174G interleukin-6 promoter polymorphism interact in predicting type 2 diabetes

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study

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21 January 2018

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

KORA-gen--resource for population genetics, controls and a broad spectrum of disease phenotypes

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https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

KORA--a research platform for population based health research

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https://api.crossref.org/works/10.1080%2F07853890802337037

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The MONICA Augsburg surveys--basis for prospective cohort studies

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21 January 2018

High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening. The KORA survey 2000.

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21 January 2018

A comprehensive linkage analysis for myocardial infarction and its related risk factors

1 reference

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21 January 2018

A common functional variant in the interleukin-6 gene is associated with increased body mass index in subjects with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1080%2F07853890802337037

21 January 2018

No association of interleukin-6 gene polymorphism (-174 G/C) with myocardial infarction or traditional cardiovascular risk factors

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21 January 2018

Significant association of the interleukin-6 gene polymorphisms C-174G and A-598G with type 2 diabetes

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21 January 2018

The -174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication?

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31 October 2018

Upregulation of reactive oxygen species generation and phagocytosis, and increased apoptosis in human neutrophils during severe sepsis and septic shock

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31 October 2018

Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans.

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31 October 2018

The interleukin-6 (-174) G/C promoter polymorphism is associated with type-2 diabetes mellitus in Native Americans and Caucasians.

1 reference

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31 October 2018

Interleukin-6 enhances glucose transport in 3T3-L1 adipocytes

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31 October 2018

Sex Differences in the Prediction of Type 2 Diabetes by Inflammatory Markers: Results from the MONICA/KORA Augsburg case-cohort study, 1984-2002

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21 January 2018

Interleukin-6 gene polymorphism -174G/C influences plasma lipid levels in women

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12 December 2020

based on heuristic

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Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18752089

12 December 2020

based on heuristic

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Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18752089

12 December 2020

based on heuristic

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Interleukin-6 gene polymorphisms and susceptibility to myocardial infarction: the ECTIM study. Etude Cas-Témoin de l'Infarctus du Myocarde

1 reference

https://pubmed.ncbi.nlm.nih.gov/18752089

12 December 2020

based on heuristic

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The promoter polymorphism of the interleukin-6 gene regulates interleukin-6 production in neonates but not in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/18752089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/07853890802337037

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

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