Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria (Q33359552)

26 July 2017

title

Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria (English)

1 reference

Plasmodium falciparum malaria

26 July 2017

main subject

phase I clinical trial

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Plasmodium falciparum

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malaria

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1 reference

1 reference

Michael P Fay

7

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Allan Saul

object named as

Allan Saul

8

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Kazutoyo Miura

3

object named as

Kazutoyo Miura

1 reference

26 July 2017

13

Carole A Long

1 reference

26 July 2017

2

Ruth D Ellis

1 reference

26 July 2017

14

Louis H Miller

1 reference

26 July 2017

4

Elissa Malkin

1 reference

26 July 2017

1

Gregory E D Mullen

1 reference

26 July 2017

10

Kelly Rausch

1 reference

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11

Samuel Moretz

1 reference

26 July 2017

9

Daming Zhu

1 reference

26 July 2017

Caroline Nolan

5

1 reference

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Mhorag Hay

6

1 reference

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Hong Zhou

12

1 reference

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John Treanor

15

1 reference

26 July 2017

language of work or name

English

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publication date

13 August 2008

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26 July 2017

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26 July 2017

volume

3

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26 July 2017

issue

8

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26 July 2017

page(s)

e2940

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Creative Commons CC0 License

26 July 2017

copyright license

start time

13 August 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

Population structure of the genes encoding the polymorphic Plasmodium falciparum apical membrane antigen 1: implications for vaccine design

1 reference

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A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits

21 June 2018

1 reference

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children

21 June 2018

1 reference

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Apical membrane antigen 1: a malaria vaccine candidate in review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Structural basis of antigenic escape of a malaria vaccine candidate

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Enhanced antibody production in mice to the malaria antigen AMA1 by CPG 7909 requires physical association of CpG and antigen

21 June 2018

1 reference

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Formulation of vaccines containing CpG oligonucleotides and alum

21 June 2018

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Malaria vaccines: are we getting closer?

21 June 2018

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A review of human vaccine research and development: malaria

21 June 2018

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CpG oligonucleotides accelerate and boost the immune response elicited by AVA, the licensed anthrax vaccine

21 June 2018

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Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

The pathogenesis of infertility and early pregnancy loss in polycystic ovary syndrome

21 June 2018

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Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria

21 June 2018

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In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response

21 June 2018

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Independent translocation of two micronemal proteins in developing Plasmodium falciparum merozoites

21 June 2018

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Antinuclear antibody testing

21 June 2018

1 reference

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Strong diversifying selection on domains of the Plasmodium falciparum apical membrane antigen 1 gene

21 June 2018

1 reference

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Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Immunisation with recombinant AMA-1 protects mice against infection with Plasmodium chabaudi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Diversity of the vaccine candidate AMA-1 of Plasmodium falciparum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

The rheumatoid factor: an analysis of clinical utility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Polymorphism in the gene encoding the apical membrane antigen-1 (AMA-1) of Plasmodium falciparum. X. Asembo Bay Cohort Project

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002940

CPG 7909 adjuvant improves hepatitis B virus vaccine seroprotection in antiretroviral-treated HIV-infected adults.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002940

Enhancement of functional antibody responses to AMA1-C1/Alhydrogel, a Plasmodium falciparum malaria vaccine, with CpG oligodeoxynucleotide

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002940

Protective immunity induced in squirrel monkeys with recombinant apical membrane antigen-1 of Plasmodium fragile.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2491586

Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18698359

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18698359

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CPG 7909, an immunostimulatory TLR9 agonist oligodeoxynucleotide, as adjuvant to Engerix-B HBV vaccine in healthy adults: a double-blind phase I/II study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18698359

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0002940

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference