A synthetic mammalian gene circuit reveals antituberculosis compounds (Q33351251)

26 July 2017

A synthetic mammalian gene circuit reveals antituberculosis compounds (English)

1 reference

26 July 2017

8

Martin Fussenegger

1 reference

26 July 2017

1

Wilfried Weber

1 reference

26 July 2017

6

Marie Daoud-El Baba

1 reference

26 July 2017

Ronald G Schoenmakers

series ordinal

2

object named as

Ronald Schoenmakers

1 reference

26 July 2017

3

Bettina Keller

1 reference

26 July 2017

4

Marc Gitzinger

1 reference

26 July 2017

Thomas Grau

5

1 reference

26 July 2017

Peter Sander

series ordinal

7

1 reference

26 July 2017

language of work or name

English

0 references

publication date

9 July 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

1 reference

26 July 2017

105

1 reference

26 July 2017

9994-9998

1 reference

26 July 2017

29

1 reference

A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Synthetic ecosystems based on airborne inter- and intrakingdom communication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

A synthetic time-delay circuit in mammalian cells and mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Mechanism of thioamide drug action against tuberculosis and leprosy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

An excitable gene regulatory circuit induces transient cellular differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Hysteresis in a synthetic mammalian gene network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Lipoprotein processing is required for virulence of Mycobacterium tuberculosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Genetic regulatory mechanisms in the synthesis of proteins

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

21 June 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Engineered gene circuits.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Advanced modular self-inactivating lentiviral expression vectors for multigene interventions in mammalian cells and in vivo transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Population pharmacokinetics of ethionamide in patients with tuberculosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Macrolide-based transgene control in mammalian cells and mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

SAMY, a novel mammalian reporter gene derived from Bacillus stearothermophilus alpha-amylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Activation of the pro-drug ethionamide is regulated in mycobacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Clinical pharmacokinetics of the antituberculosis drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

The Neurotoxicity of Antibacterial Agents

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Global trends in resistance to antituberculosis drugs. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800663105

Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800663105

An engineered epigenetic transgene switch in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800663105

Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800663105

Broad-spectrum protein biosensors for class-specific detection of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0800663105

Binding of four repressors to double-stranded tet operator region stabilizes it against thermal denaturation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481315

Acute hepatic necrosis associated with ethionamide

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18621677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding characteristics of Escherichia coli biotin repressor-operator complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18621677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0800663105

1 reference

release_uapkzqsln5a2zp4ij4dducvgk4

26 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uapkzqsln5a2zp4ij4dducvgk4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

2481315

1 reference

26 July 2017

1 reference