Alternative binding proteins: biological activity and therapeutic potential of cystine-knot miniproteins (Q33330734)

25 July 2017

1 reference

title

Alternative binding proteins: biological activity and therapeutic potential of cystine-knot miniproteins (English)

1 reference

25 July 2017

Harald Kolmar

1

1 reference

PubMed ID

18435757

25 July 2017

language of work or name

English

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publication date

24 April 2008

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25 July 2017

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25 July 2017

275

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25 July 2017

11

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25 July 2017

2684-2690

1 reference

Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate.

25 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Oxidative folding of cyclic cystine knot proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Oxidative folding of the cystine knot motif in cyclotide proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Folding of omega-conotoxins. 2. Influence of precursor sequences and protein disulfide isomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Sequence requirements of the GPNG beta-turn of the Ecballium elaterium trypsin inhibitor II explored by combinatorial library screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The KNOTTIN website and database: a new information system dedicated to the knottin scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Structure of Ecballium elaterium trypsin inhibitor II (EETI-II): a rigid molecular scaffold.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Refined solution structure of omega-conotoxin GVIA: implications for calcium channel binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin MVIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

N-type calcium channel blockers: novel therapeutics for the treatment of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Intrathecal ziconotide for refractory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Chemical modification of conotoxins to improve stability and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

SNX-111, a novel, presynaptic N-type calcium channel antagonist, is neuroprotective against focal cerebral ischemia in rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Spider toxins activate the capsaicin receptor to produce inflammatory pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Squash inhibitors: from structural motifs to macrocyclic knottins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

NMR structure of a minimized human agouti related protein prepared by total chemical synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Current trends in the structure-activity relationship studies of the endogenous agouti-related protein (AGRP) melanocortin receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Insecticidal plant cyclotides and related cystine knot toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Triterpenoid saponins from Bellium bellidioides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Cytotoxic cyclotides from Viola tricolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Reversible antifouling effect of the cyclotide cycloviolacin O2 against barnacles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The cystine knot of a squash-type protease inhibitor as a structural scaffold for Escherichia coli cell surface display of conformationally constrained peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Platelet glycoprotein IIb/IIIa receptor blockade in coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Display of passenger proteins on the surface of Escherichia coli K-12 by the enterohemorrhagic E. coli intimin EaeA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Grafting of thrombopoietin-mimetic peptides into cystine knot miniproteins yields high-affinity thrombopoietin antagonists and agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Mast cell tryptase beta as a target in allergic inflammation: an evolving story

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Head-to-tail cyclized cystine-knot peptides by a combined recombinant and chemical route of synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Identification of epitope-like consensus motifs using mRNA display

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

New binding specificities derived from Min-23, a small cystine-stabilized peptidic scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

Design and Characterization of a Hybrid Miniprotein That Specifically Inhibits Porcine Pancreatic Elastase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06440.X

10.1111/J.1742-4658.2008.06440.X

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference

PubMed ID

18435757