Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis (Q33322191)

25 July 2017

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis (English)

1 reference

amyotrophic lateral sclerosis

25 July 2017

0 references

author name string

Edor Kabashi

1

1 reference

25 July 2017

Jeffrey N Agar

2

1 reference

25 July 2017

Yu Hong

3

1 reference

25 July 2017

David M Taylor

4

1 reference

25 July 2017

Sandra Minotti

5

1 reference

25 July 2017

Denise A Figlewicz

6

1 reference

25 July 2017

Heather D Durham

7

1 reference

25 July 2017

language of work or name

English

0 references

publication date

1 June 2008

1 reference

Journal of Neurochemistry

25 July 2017

14

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

25 July 2017

105

1 reference

25 July 2017

6

1 reference

25 July 2017

2353-2366

1 reference

The proteasome: paradigm of a self-compartmentalizing protease

25 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Onset and progression in inherited ALS determined by motor neurons and microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Unraveling the mechanisms involved in motor neuron degeneration in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Two-dimensional Blue native/SDS gel electrophoresis of multi-protein complexes from whole cellular lysates: a proteomics approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Impact of ageing on proteasome structure and function in human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

The proteasome, a novel protease regulated by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Proteasomal degradation of mutant superoxide dismutases linked to amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Characterization of the proteasome using native gel electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Interferon-gamma inducible exchanges of 20S proteasome active site subunits: why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Pathogenic superoxide dismutase structure, folding, aggregation and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Proteasome inhibition enhances the stability of mouse Cu/Zn superoxide dismutase with mutations linked to familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Failure of protein quality control in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Decreased levels of proteasome activity and proteasome expression in aging spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

How do ALS-associated mutations in superoxide dismutase 1 promote aggregation of the protein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Mutant Cu/Zn-superoxide dismutase proteins have altered solubility and interact with heat shock/stress proteins in models of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

High molecular weight complexes of mutant superoxide dismutase 1: age-dependent and tissue-specific accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05317.X

10.1111/J.1471-4159.2008.05317.X

21 January 2018

Identifiers

DOI

1 reference

25 July 2017

1 reference