Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships (Q33316208)

25 July 2017

Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships (English)

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25 July 2017

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Nicholas D Bland

1

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25 July 2017

John W Pinney

2

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25 July 2017

Josie E Thomas

3

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25 July 2017

Anthony J Turner

4

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25 July 2017

R Elwyn Isaac

5

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25 July 2017

23 January 2008

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25 July 2017

BMC Evolutionary Biology

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25 July 2017

8

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25 July 2017

16

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https://scigraph.springernature.com/pub.10.1186/1471-2148-8-16

25 July 2017

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Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP)

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Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function

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A three-dimensional model of the neprilysin 2 active site based on the X-ray structure of neprilysin. Identification of residues involved in substrate hydrolysis and inhibitor binding of neprilysin 2

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Computer modeling and nanosecond simulation of the enzyme?substrate complex of the common lymphoblastic leukemia antigen (neprilysin) indicates shared residues at the primary specificity pocket (S1') with matrix metalloproteases

21 June 2018

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Human recombinant endopeptidase PHEX has a strict S1' specificity for acidic residues and cleaves peptides derived from fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein

21 June 2018

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The Draft Genome of Ciona intestinalis: Insights into Chordate and Vertebrate Origins

21 June 2018

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Fourfold faster rate of genome rearrangement in nematodes than in Drosophila

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

21 June 2018

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21 June 2018

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Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.

21 June 2018

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Caenorhabditis elegans neprilysin NEP-1: an effector of locomotion and pharyngeal pumping

31 October 2018

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Global gene expression analysis of Anopheles gambiae responses to microbial challenge

31 October 2018

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An essential role in molting and morphogenesis of Caenorhabditis elegans for ACN-1, a novel member of the angiotensin-converting enzyme family that lacks a metallopeptidase active site

31 October 2018

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In vitro metabolism of an insect neuropeptide by homogenates of the nematode Caenorhabditis elegans

31 October 2018

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Identification and localization of a neprilysin-like activity that degrades tachykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and locust, Locusta migratoria

31 October 2018

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31 October 2018

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Extracellular peptidases of imaginal discs of Drosophila melanogaster

31 October 2018

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Inhibition of MEPE cleavage by Phex.

31 October 2018

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NOTUNG: a program for dating gene duplications and optimizing gene family trees

31 October 2018

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Molecular modelling and site-directed mutagenesis of the active site of endothelin-converting enzyme.

31 October 2018

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CTree: comparison of clusters between phylogenetic trees made easy

31 October 2018

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12 December 2020

EST analysis of the cnidarian Acropora millepora reveals extensive gene loss and rapid sequence divergence in the model invertebrates

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12 December 2020

Neutral endopeptidase-24.11 (NEP) deactivates PDGF- and TGF-beta-induced cell shape changes in invertebrate immunocytes

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12 December 2020

M13 endopeptidases: New conserved motifs correlated with structure, and simultaneous phylogenetic occurrence of PHEX and the bony fish

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12 December 2020

Differential loss of ancestral gene families as a source of genomic divergence in animals

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12 December 2020

Downregulation of enkephalin-mediated inflammatory responses by CDl0/neutral endopeptidase 24.11

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12 December 2020

Identifiers

DOI

10.1186/1471-2148-8-16

1 reference

Dimensions Publication ID

25 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2148-8-16

9 September 2019

1 reference

25 July 2017

1 reference