Hsp90 inhibition decreases mitochondrial protein turnover (Q33303676)

25 July 2017

Hsp90 inhibition decreases mitochondrial protein turnover (English)

1 reference

25 July 2017

1 reference

4

David M Hockenbery

1 reference

25 July 2017

Daciana H Margineantu

series ordinal

1

1 reference

25 July 2017

Christine B Emerson

series ordinal

2

1 reference

25 July 2017

Dolores Diaz

series ordinal

3

1 reference

25 July 2017

language of work or name

English

0 references

publication date

24 October 2007

1 reference

25 July 2017

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25 July 2017

2

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25 July 2017

e1066

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25 July 2017

10

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Creative Commons Attribution 4.0 International

25 July 2017

start time

24 October 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

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Quantitative monitoring of autophagic degradation.

28 July 2018

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Turning off estrogen receptor beta-mediated transcription requires estrogen-dependent receptor proteolysis.

28 July 2018

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Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells

28 July 2018

1 reference

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Proteasome inhibition induces differential heat shock protein response but not unfolded protein response in HepG2 cells

28 July 2018

1 reference

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Erythroid-specific 5-aminolevulinate synthase protein is stabilized by low oxygen and proteasomal inhibition

28 July 2018

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Large-scale analysis of the human ubiquitin-related proteome

28 July 2018

1 reference

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Signaling through monoubiquitination.

28 July 2018

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Targeting multiple signal transduction pathways through inhibition of Hsp90.

28 July 2018

1 reference

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Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates: roles of endoplamic reticulum-bound p97/Cdc48p and proteasome

28 July 2018

1 reference

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Flow cytometry and GFP: A novel assay for measuring the import and turnover of nuclear‐encoded mitochondrial proteins in live PC12 cells

28 July 2018

1 reference

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A proteomics approach to understanding protein ubiquitination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control

28 July 2018

1 reference

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Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

ER-associated degradation in protein quality control and cellular regulation

28 July 2018

1 reference

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ErbB2 overexpression in an ovarian cancer cell line confers sensitivity to the HSP90 inhibitor geldanamycin

28 July 2018

1 reference

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The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy

28 July 2018

1 reference

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Cytochrome c oxidase-deficient patients have distinct subunit assembly profiles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells

28 July 2018

1 reference

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Flow cytometric measurement of mitochondrial mass and function: a novel method for assessing chemoresistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

A novel fluorescent marker for assembled mitochondria ATP synthase of yeast. OSCP subunit fused to green fluorescent protein is assembled into the complex in vivo

28 July 2018

1 reference

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Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Two-dimensional gel electrophoretic resolution of the polypeptides of rat liver mitochondria and the outer membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Dynamics, structure, and function are coupled in the mitochondrial matrix

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Regulation of 17-AAG-induced apoptosis: role of Bcl-2, Bcl-XL, and Bax downstream of 17-AAG-mediated down-regulation of Akt, Raf-1, and Src kinases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Hyperubiquitination of proteins in dilated cardiomyopathy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

c-MYC apoptotic function is mediated by NRF-1 target genes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3'-kinase-AKT-dependent pathway.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Multidimensional Protein Identification Technology (MudPIT) Analysis of Ubiquitinated Proteins in Plants

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2031825

Degradation of unassembled soluble Ig subunits by cytosolic proteasomes: evidence that retrotranslocation and degradation are coupled events

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17957250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A proteomics approach to identify the ubiquitinated proteins in mouse heart

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17957250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endoplasmic reticulum-associated protein degradation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17957250

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0001066

1 reference

25 July 2017

0 references

1 reference

25 July 2017

1 reference