Tailoring structure-function properties of L-asparaginase: engineering resistance to trypsin cleavage (Q33274867)

15 October 2017

Tailoring structure-function properties of L-asparaginase: engineering resistance to trypsin cleavage (English)

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15 October 2017

3

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15 October 2017

Georgia A Kotzia

1

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15 October 2017

Katerina Lappa

series ordinal

2

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15 October 2017

language of work or name

English

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publication date

1 June 2007

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15 October 2017

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15 October 2017

404

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15 October 2017

2

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15 October 2017

337-343

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Crystallization and preliminary crystallographic analysis of L-asparaginase from Erwinia carotovora

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

PEGylation, successful approach to drug delivery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Recombinant protein therapeutics--success rates, market trends and values to 2010.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Effect of pegylation on pharmaceuticals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Polyethylene glycol-interferon: current status in hepatitis C virus therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Effects of PEG conjugation on insulin properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Chemistry for peptide and protein PEGylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Do bacterial L-asparaginases utilize a catalytic triad Thr-Tyr-Glu?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Structural basis for the activity and substrate specificity of Erwinia chrysanthemi L-asparaginase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Peptide and protein PEGylation: a review of problems and solutions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Construction and structural modeling of a single-chain Fv-asparaginase fusion protein resistant to proteolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Bioconjugation in pharmaceutical chemistry.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

L-asparaginase and PEG asparaginase--past, present, and future

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Polymers for delivering peptides and proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Erwinia chrysanthemi L-asparaginase: epitope mapping and production of antigenically modified enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Biomedical and biotechnological applications of PEG- and PM-modified proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

PEG-ADA: an alternative to haploidentical bone marrow transplantation and an adjunct to gene therapy for adenosine deaminase deficiency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

WHAT IF: a molecular modeling and drug design program

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Comparative study on conformational stability and subunit interactions of two bacterial asparaginases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Cloning, expression and characterisation of Erwinia carotovora L-asparaginase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Chemical modification of L-asparaginase from Escherichia coli with a modified polyethyleneglycol under substrate protection conditions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

One-step purification and kinetic properties of the recombinant L-asparaginase from Erwinia carotovora

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Effects of polyethylene glycol attachment on physicochemical and biological stability of E. coli L-asparaginase.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Crystallization and preliminary crystallographic studies of five crystal forms of Escherichia coli L-asparaginase II (Asp90Glu mutant).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Structural and functional stabilization of L-asparaginase via multisubunit immobilization onto highly activated supports

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Stabilization of L-asparaginase modified with comb-shaped poly(ethylene glycol) derivatives, in vivo and in vitro.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1868801

Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor

31 October 2018

1 reference

12 December 2020

Solid-phase enzyme modification via affinity chromatography

1 reference

12 December 2020

L-asparaginase from Erwinia carotovora. Substrate specificity and enzymatic properties

1 reference

12 December 2020

L-Asparaginase from escherichia coli B. Succinylation and subunit interactions

1 reference

12 December 2020

An improved 2,4,6-trinitrobenzenesulfonic acid method for the determination of amines

1 reference

12 December 2020

Modification of human hemoglobin with polyethylene glycol : a new candidate for blood substitute

1 reference

12 December 2020

Physicochemical characterization of PEG-PPG conjugated human urokinase

1 reference

12 December 2020

High and constant plasma levels of tissue plasminogen activator and PEG-hirudin can be achieved by subcutaneous delivery

1 reference

12 December 2020

Synthesis and characterization of high-molecular mass polyethylene glycol-conjugated oligonucleotides

1 reference

12 December 2020

Increased serum trypsin and elastase-1 levels in patients undergoing L-asparaginase therapy

1 reference

12 December 2020

TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI

1 reference

12 December 2020

A new procedure for the synthesis of polyethylene glycol-protein adducts; Effects on function, receptor recognition, and clearance of superoxide dismutase, lactoferrin, and α2-macroglobulin

1 reference

12 December 2020

L-asparaginase from Erwinia carotovora. An improved recovery and purification process using affinity chromatography

1 reference

12 December 2020

Phospholipase D modified with a polyethylene glycol derivative

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ20061708

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15 October 2017

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15 October 2017

PubMed publication ID

17313368

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