Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase (Q33268317)

24 July 2017

Identification and biochemical studies on novel non-nucleoside inhibitors of the enzyme adenosine kinase (English)

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24 July 2017

Jae Park

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24 July 2017

Gayathri Vaidyanathan

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2

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24 July 2017

Bhag Singh

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3

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24 July 2017

Radhey S Gupta

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4

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24 July 2017

language of work or name

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1 April 2007

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24 July 2017

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24 July 2017

26

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24 July 2017

203-212

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24 July 2017

3

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https://scigraph.springernature.com/pub.10.1007/s10930-006-9062-z

24 July 2017

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cites work

Nucleoside and nucleobase transport systems of mammalian cells

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Crossref

https://api.crossref.org/works/10.1007%2FS10930-006-9062-Z

Bicyclic nucleoside inhibitors of varicella-zoster virus modified on the sugar moiety: 3' and 5' derivatives.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10930-006-9062-Z

The role of adenosine kinase in regulating adenosine concentration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10930-006-9062-Z

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive eff

21 January 2018

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12 December 2020

Adenosine kinase inhibitors as a novel approach to anticonvulsant therapy.

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12 December 2020

Pentavalent ions dependency is a conserved property of adenosine kinase from diverse sources: identification of a novel motif implicated in phosphate and magnesium ion binding and substrate inhibition.

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12 December 2020

Challenges in developing P2 purinoceptor-based therapeutics

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12 December 2020

Adenosine kinase inhibitors augment release of adenosine from spinal cord slices

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12 December 2020

Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor..

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12 December 2020

Pentavalent ions dependency of mammalian adenosine kinase

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12 December 2020

Characterization of the effects of adenosine kinase inhibitors on acute thermal nociception in mice

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12 December 2020

New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation

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12 December 2020

Receptors for purines and pyrimidines

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12 December 2020

Therapeutic potential of adenosine kinase inhibitors

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12 December 2020

Adenosine: The prototypic neuromodulator

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12 December 2020

Genetic and biochemical studies with the adenosine analogs toyocamycin and tubercidin: Mutation at the adenosine kinase locus in Chinese hamster cells

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12 December 2020

Structural requirements for activity of nucleosides as substrates for adenosine kinase: orientation of substituents on the pentofuranosyl ring

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12 December 2020

Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species. High frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene

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12 December 2020

Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine

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12 December 2020

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs

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12 December 2020

Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues

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12 December 2020

Pre- and peristroke treatment with the adenosine kinase inhibitor, 5'-deoxyiodotubercidin, significantly reduces infarct volume after temporary occlusion of the middle cerebral artery in rats.

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12 December 2020

Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices

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12 December 2020

Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases

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12 December 2020

Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart

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12 December 2020

Adenosine kinase inhibition protects brain against transient focal ischemia in rats.

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12 December 2020

Structure-activity studies on mammalian adenosine kinase.

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12 December 2020

Purinergic and pyrimidinergic receptors as potential drug targets

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12 December 2020

Phosphorylated derivatives that activate or inhibit mammalian adenosine kinase provide insights into the role of pentavalent ions in AK catalysis

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12 December 2020

Turnover of adenosine in plasma of human and dog blood

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12 December 2020

Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues

1 reference

12 December 2020

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat

1 reference

12 December 2020

Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives

1 reference

12 December 2020

Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo[2,3-d]pyrimidine nucleoside analogues

1 reference

12 December 2020

10.1007/S10930-006-9062-Z

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DOI

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24 July 2017

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