Efficient neutralization of anthrax toxin by chimpanzee monoclonal antibodies against protective antigen (Q33232901)

24 July 2017

title

Efficient neutralization of anthrax toxin by chimpanzee monoclonal antibodies against protective antigen (English)

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24 July 2017

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Peter Schuck

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Stephen H. Leppla

4

object named as

Stephen Leppla

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Mahtab Moayeri

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Marisa St Claire

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Suzanne Emerson

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Robert Purcell

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Zhaochun Chen

1

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Yi-Hua Zhou

3

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Andrew Sebrell

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Fujuan Yu

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Juraj Svitel

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language of work or name

English

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publication date

2 February 2006

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Journal of Infectious Diseases

24 July 2017

published in

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volume

193

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issue

5

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24 July 2017

page(s)

625-633

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Identification of a receptor-binding region within domain 4 of the protective antigen component of anthrax toxin

24 July 2017

cites work

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12 December 2020

Potential of primate monoclonal antibodies to substitute for human antibodies: nucleotide sequence of chimpanzee Fab fragments.

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12 December 2020

Crystal structure of the anthrax toxin protective antigen

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12 December 2020

Screening of phage antibody libraries

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12 December 2020

Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalization

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12 December 2020

Alanine-scanning mutations in domain 4 of anthrax toxin protective antigen reveal residues important for binding to the cellular receptor and to a neutralizing monoclonal antibody

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12 December 2020

Production of monoclonal antibodies in COS and CHO cells

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12 December 2020

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system

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12 December 2020

Functional analysis of Bacillus anthracis protective antigen by using neutralizing monoclonal antibodies

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12 December 2020

A definitive set of oligonucleotide primers for amplifying human V regions

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12 December 2020

Human antibodies from immunized donors are protective against anthrax toxin in vivo

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12 December 2020

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12 December 2020

The human immunoglobulin VH repertoire

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12 December 2020

Antigen specificity and tumour targeting efficiency of a human carcinoembryonic antigen-specific scFv and affinity-matured derivatives

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12 December 2020

Increased affinity leads to improved selective tumor delivery of single-chain Fv antibodies

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12 December 2020

Combined affinity and rate constant distributions of ligand populations from experimental surface binding kinetics and equilibria.

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12 December 2020

Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis

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12 December 2020

Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine

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12 December 2020

Human anti-anthrax protective antigen neutralizing monoclonal antibodies derived from donors vaccinated with anthrax vaccine adsorbed

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12 December 2020

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity.

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12 December 2020

The role of antibody concentration and avidity in antiviral protection.

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12 December 2020

Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules.

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12 December 2020

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12 December 2020

Human and primate monoclonal antibodies for in vivo therapy

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Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque

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12 December 2020

Antiidiotypic vaccination against murine coronavirus infection

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12 December 2020

Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin.

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12 December 2020

Protection from lethal coronavirus infection by immunoglobulin fragments

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12 December 2020

Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies.

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12 December 2020

Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity

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12 December 2020

In vitro correlate of immunity in a rabbit model of inhalational anthrax

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12 December 2020

A high-affinity monoclonal antibody to anthrax protective antigen passively protects rabbits before and after aerosolized Bacillus anthracis spore challenge

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12 December 2020

Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies

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12 December 2020

Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus

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12 December 2020

Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors

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12 December 2020

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo

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12 December 2020

Passive protection by polyclonal antibodies against Bacillus anthracis infection in guinea pigs

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12 December 2020

Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization

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12 December 2020

Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein

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12 December 2020

Identifiers

DOI

10.1086/500148

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24 July 2017

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