Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A. (Q33230386)

24 July 2017

Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A. (English)

1 reference

24 July 2017

1 reference

Saba Choudhary

1

1 reference

24 July 2017

Kevin M Doherty

2

1 reference

24 July 2017

Christopher J Handy

3

1 reference

24 July 2017

Jane M Sayer

4

1 reference

24 July 2017

Haruhiko Yagi

5

1 reference

24 July 2017

Donald M Jerina

6

1 reference

24 July 2017

Robert M Brosh

7

1 reference

24 July 2017

language of work or name

English

0 references

publication date

27 December 2005

1 reference

Journal of Biological Chemistry

24 July 2017

1 reference

24 July 2017

281

1 reference

24 July 2017

6000-6009

1 reference

24 July 2017

9

1 reference

The DNA damage response: putting checkpoints in perspective

24 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Mechanisms of helicase-catalyzed DNA unwinding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Crawling and wiggling on DNA: structural insights to the mechanism of DNA unwinding by helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Structure and function of hexameric helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Homologous recombination is elevated in some Werner-like syndromes but not during normal in vitro or in vivo senescence of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Loss of Werner syndrome protein function promotes aberrant mitotic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Homologous recombination resolution defect in werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

RecQ helicases: caretakers of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Junction of RecQ helicase biochemistry and human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

RecQ helicases: multiple roles in genome maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Metabolism of benzo[a]pyrene. VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

NMR solution structures of stereoisometric covalent polycyclic aromatic carcinogen-DNA adduct: principles, patterns, and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Multiple conformations of an intercalated (-)-(7S,8R,9S, 10R)-N6-[10-(7,8,9,10-tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct in the N-ras codon 61 sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Base pair conformation-dependent excision of benzo[a]pyrene diol epoxide-guanine adducts by human nucleotide excision repair enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Nucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Effects of base sequence context on translesion synthesis past a bulky (+)-trans-anti-B[a]P-N2-dG lesion catalyzed by the Y-family polymerase pol kappa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

trans-Lesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

O(6)-allyl protected deoxyguanosine adducts of polycyclic aromatic hydrocarbons as building blocks for the synthesis of oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Position-specific trapping of topoisomerase II by benzo[a]pyrene diol epoxide adducts: implications for interactions with intercalating anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Interactions of DNA helicases with damaged DNA: possible biological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Inhibition of Werner syndrome helicase activity by benzo[c]phenanthrene diol epoxide dA adducts in DNA is both strand-and stereoisomer-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Synthesis and characterization of site-specific and stereoisomeric fjord dibenzo[a,l]pyrene diol epoxide-N(6)-adenine adducts: unusual thermal stabilization of modified DNA duplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

DNA binding and nucleotide flipping by the human DNA repair protein AGT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Asymmetry of DNA replication fork progression in Werner's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

RPA alleviates the inhibitory effect of vinylphosphonate internucleotide linkages on DNA unwinding by BLM and WRN helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M510122200

21 January 2018

Identifiers

DOI

10.1074/JBC.M510122200

1 reference

24 July 2017

1 reference