Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks (Q33223660)

24 July 2017

Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks (English)

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G protein-coupled receptor

24 July 2017

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artificial neural network

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Pantelis G Bagos

2

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Stavros J Hamodrakas

series ordinal

3

object named as

Stavros J Hamodrakas

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24 July 2017

Nikolaos G Sgourakis

1

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PubMed ID

16174684

24 July 2017

language of work or name

English

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publication date

20 September 2005

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24 July 2017

6

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based on heuristic

inferred from page(s)

published in

Bioinformatics

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24 July 2017

21

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24 July 2017

22

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24 July 2017

4101-4106

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Adenylyl cyclase functions downstream of the Galpha protein Gpa1 and controls mating and pathogenicity of Cryptococcus neoformans

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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The G-protein-coupled receptor GCR1 regulates DNA synthesis through activation of phosphatidylinositol-specific phospholipase C.

21 January 2018

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The selection and design of GPCR ligands: from concept to the clinic

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Combining evidence using p-values: application to sequence homology searches

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A highly sensitive selection method for directed evolution of homing endonucleases

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The Pfam protein families database

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A naive Bayes model to predict coupling between seven transmembrane domain receptors and G-proteins.

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Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.

21 January 2018

1 reference

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Profile hidden Markov models

21 January 2018

1 reference

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A database for G proteins and their interaction with GPCRs

21 January 2018

1 reference

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Single amino acid substitutions and deletions that alter the G protein coupling properties of the V2 vasopressin receptor identified in yeast by receptor random mutagenesis

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Integrative bioinformatics for functional genome annotation: trawling for G protein-coupled receptors

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The repertoire of G-protein-coupled receptors in fully sequenced genomes

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Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors

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G protein-coupled receptors in Anopheles gambiae

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Galpha(14) links a variety of G(i)- and G(s)-coupled receptors to the stimulation of phospholipase C

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GPCRDB information system for G protein-coupled receptors

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G-protein-coupled signaling in Arabidopsis

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Plants: the latest model system for G-protein research

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Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function

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Novel G-protein-coupled receptor-like proteins in the plant pathogenic fungus Magnaporthe grisea

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Molecular cloning and characterization of a novel Gq-coupled orphan receptor GPRg1 exclusively expressed in the central nervous system

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Yeast system as a screening tool for pharmacological assessment of g protein coupled receptors

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Evaluation of methods for the prediction of membrane spanning regions

21 January 2018

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The art of pedigree drawing: algorithmic aspects.

21 January 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

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The Arabidopsis putative G protein-coupled receptor GCR1 interacts with the G protein alpha subunit GPA1 and regulates abscisic acid signaling

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A novel method for GPCR recognition and family classification from sequence alone using signatures derived from profile hidden Markov models.

21 January 2018

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Receptors coupled to heterotrimeric G proteins of the G12 family

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1 reference

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Effects of mutations in the N terminal region of the yeast G protein alpha-subunit Gpa1p on signaling by pheromone receptors

21 January 2018

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Virally encoded 7TM receptors

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A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models

21 January 2018

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21 January 2018

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Predicting GPCR-G-protein coupling using hidden Markov models.

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions

21 January 2018

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G protein selectivity is regulated by multiple intracellular regions of GPCRs

21 January 2018

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GRIFFIN: a system for predicting GPCR-G-protein coupling selectivity using a support vector machine and a hidden Markov model

21 January 2018

1 reference

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10.1093/BIOINFORMATICS/BTI679

21 January 2018

Identifiers

DOI

1 reference

journals/bioinformatics/SgourakisBH05

24 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

PubMed ID

16174684