sirolimus Béarla (Q32089)

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pharmaceutical drug Béarla
cuir in eagar
Language Label Description Also known as
Gaeilge
No label defined
No description defined
    Béarla
    sirolimus
    pharmaceutical drug
    • rapamycin
    • WY-090217
    • AY-22989
    • (-)-rapamycin

    Statements

    fo-aicme de
    alcalóideach
    0 references
    (32RS)-rapamycin Béarla
    0 references
    úsáid
    cógas
    1 reference
    teideal
    Sirolimus (Béarla)
    ráite i
    DrugBank Béarla
    teanga an tsaothair nó an ainm
    Béarla
    dáta foilsithe
    17 Samhain 2015
    DrugBank ID Béarla
    00877
    mais
    913.555142 aonad maise adamhaí
    1 reference
    ráite i
    PubChem Béarla
    PubChem CID Béarla
    5284616
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Rapamycin (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    foirmle cheimiceach
    C₅₁H₇₉NO₁₃
    1 reference
    ráite i
    PubChem Béarla
    PubChem CID Béarla
    5284616
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Rapamycin (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    SMILES canónta
    CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
    1 reference
    ráite i
    PubChem Béarla
    PubChem CID Béarla
    5284616
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Rapamycin (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    SMILES isiméireach
    CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)OC)CC[C@H]1O
    1 reference
    ráite i
    Global Substance Registration System Béarla
    UNII Béarla
    W36ZG6FT64
    dáta rochtana
    14 Feabhra 2018
    active ingredient in Béarla
    Rapamune Béarla
    1 reference
    ráite i
    RxNorm Béarla
    RxNorm ID Béarla
    258355
    dáta rochtana
    14 Feabhra 2018
    World Health Organisation international non-proprietary name Béarla
    sirolimus (Béarla)
    1 reference
    ráite i
    ChEMBL Béarla
    ChEMBL ID Béarla
    CHEMBL413
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Sirolimus (Béarla)
    dáta rochtana
    19 Eanáir 2016
    tacsón ina n-aimsítear é
    Streptomyces hygroscopicus
    19 references
    ráite i
    Incorporation of acetate, propionate, and methionine into rapamycin by Streptomyces hygroscopicus Béarla
    ráite i
    Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization. Béarla
    ráite i
    Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. Béarla
    ráite i
    Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2). Béarla
    ráite i
    Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. Béarla
    ráite i
    A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors. Béarla
    ráite i
    Effects of dissolved oxygen level on rapamycin production by pellet-form of Streptomyces hygroscopicus Béarla
    ráite i
    Studies on process optimization methods for rapamycin production using Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Production of rapamycin in Streptomyces hygroscopicus from glycerol-based media optimized by systemic methodology Béarla
    ráite i
    Draft Genome Sequence of Streptomyces iranensis. Béarla
    ráite i
    Discovery of actinoplanic acid pathway in reveals a genetically conserved synergism with rapamycin Béarla
    ráite i
    Carbon source nutrition of rapamycin biosynthesis in Streptomyces hygroscopicus Béarla
    ráite i
    Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase Béarla
    ráite i
    An amplifiable and deletable locus of Streptomyces ambofaciens RP181110 contains a very large gene homologous to polyketide synthase genes Béarla
    ráite i
    The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus. Béarla
    ráite i
    Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus Béarla
    ráite i
    A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain Béarla
    ráite i
    Isolation and structure of homotemsirolimuses A, B, and C. Béarla
    Streptomyces iranensis
    16 references
    ráite i
    Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. Béarla
    ráite i
    Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2). Béarla
    ráite i
    Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. Béarla
    ráite i
    A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors. Béarla
    ráite i
    Effects of dissolved oxygen level on rapamycin production by pellet-form of Streptomyces hygroscopicus Béarla
    ráite i
    Studies on process optimization methods for rapamycin production using Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Production of rapamycin in Streptomyces hygroscopicus from glycerol-based media optimized by systemic methodology Béarla
    ráite i
    Draft Genome Sequence of Streptomyces iranensis. Béarla
    ráite i
    Discovery of actinoplanic acid pathway in reveals a genetically conserved synergism with rapamycin Béarla
    ráite i
    Carbon source nutrition of rapamycin biosynthesis in Streptomyces hygroscopicus Béarla
    ráite i
    Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase Béarla
    ráite i
    An amplifiable and deletable locus of Streptomyces ambofaciens RP181110 contains a very large gene homologous to polyketide synthase genes Béarla
    ráite i
    The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus. Béarla
    ráite i
    Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus Béarla
    ráite i
    A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain Béarla
    Streptomyces rapamycinicus
    16 references
    ráite i
    Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. Béarla
    ráite i
    Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2). Béarla
    ráite i
    Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. Béarla
    ráite i
    A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors. Béarla
    ráite i
    Effects of dissolved oxygen level on rapamycin production by pellet-form of Streptomyces hygroscopicus Béarla
    ráite i
    Studies on process optimization methods for rapamycin production using Streptomyces hygroscopicus ATCC 29253. Béarla
    ráite i
    Production of rapamycin in Streptomyces hygroscopicus from glycerol-based media optimized by systemic methodology Béarla
    ráite i
    Draft Genome Sequence of Streptomyces iranensis. Béarla
    ráite i
    Discovery of actinoplanic acid pathway in reveals a genetically conserved synergism with rapamycin Béarla
    ráite i
    Carbon source nutrition of rapamycin biosynthesis in Streptomyces hygroscopicus Béarla
    ráite i
    Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase Béarla
    ráite i
    An amplifiable and deletable locus of Streptomyces ambofaciens RP181110 contains a very large gene homologous to polyketide synthase genes Béarla
    ráite i
    The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus. Béarla
    ráite i
    Effect of nitrogen source on biosynthesis of rapamycin by Streptomyces hygroscopicus Béarla
    ráite i
    A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain Béarla
    spriocghalar
    pachyonychia congenita Béarla
    0 references
    lymphangioleiomyomatosis Béarla
    1 reference
    ráite i
    Drug Indications Extracted from FAERS Béarla
    dáta rochtana
    2 Deireadh Fómhair 2018
    renal cell carcinoma Béarla
    0 references
    transplant rejection Béarla
    0 references
    significant drug interaction Béarla
    legal status (medicine) Béarla
    boxed warning Béarla
    1 reference
    URL tagartha
    https://nctr-crs.fda.gov/fdalabel/ui/spl-summaries/criteria/343802
    teideal
    FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links. (Béarla)
    produced by Béarla
    NCI Thesaurus ID Béarla
    C1212
    1 reference
    ráite i
    Global Substance Registration System Béarla
    UNII Béarla
    W36ZG6FT64
    dáta rochtana
    14 Feabhra 2018
    codanna
    carbón
    0 references
    hidrigin
    0 references
    ocsaigin
    0 references
    nítrigin
    0 references
    catagóir Commons
    Sirolimus
    0 references

    Identifiers

    InChIKey Béarla
    ChemSpider ID Béarla
    10482078
    1 reference
    ráite i
    ChemSpider Béarla
    ChemSpider ID Béarla
    10482078
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Sirolimus (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    PubChem CID Béarla
    5284616
    1 reference
    ráite i
    PubChem Béarla
    PubChem CID Béarla
    5284616
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Rapamycin (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    ChEBI ID Béarla
    9168
    mapping relation type Béarla
    exact match Béarla
    2 references
    ráite i
    ChEMBL Béarla
    ChEMBL ID Béarla
    CHEMBL413
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    SIROLIMUS (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    ráite i
    ChEBI release 2021-03-01 Béarla
    ChEMBL ID Béarla
    CHEMBL413
    1 reference
    ráite i
    ChEMBL Béarla
    ChEMBL ID Béarla
    CHEMBL413
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    SIROLIMUS (Béarla)
    dáta rochtana
    21 Meán Fómhair 2016
    UniChem compound ID Béarla
    123924
    1 reference
    ráite i
    UniChem Béarla
    HSDB ID Béarla
    7284
    1 reference
    ráite i
    Hazardous Substances Data Bank Béarla
    HSDB ID Béarla
    7284
    dáta foilsithe
    28 Deireadh Fómhair 2019
    teideal
    SIROLIMUS (Béarla)
    dáta rochtana
    10 Bealtaine 2021
    NSC number Béarla
    226080
    0 references
    758664
    0 references
    EC number Béarla
    610-965-5
    1 reference
    ráite i
    ECHA Substance Infocard database Béarla
    ECHA Substance Infocard ID Béarla
    100.107.147
    dáta rochtana
    27 Nollaig 2018
    teideal
    (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (Béarla)
    quotation Béarla
    CAS no.: 53123-88-9 (Béarla)
    ECHA Substance Infocard ID Béarla
    100.107.147
    1 reference
    ráite i
    ECHA Substance Infocard database Béarla
    ECHA Substance Infocard ID Béarla
    100.107.147
    dáta rochtana
    27 Nollaig 2018
    teideal
    (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (Béarla)
    quotation Béarla
    CAS no.: 53123-88-9 (Béarla)
    ATC code Béarla
    L04AA10
    1 reference
    ráite i
    DrugBank Béarla
    DrugBank ID Béarla
    00877
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Sirolimus (Béarla)
    dáta foilsithe
    17 Samhain 2015
    S01XA23
    0 references
    MeSH descriptor ID Béarla
    D020123
    luaite mar
    Sirolimus
    0 references
    MeSH tree code Béarla
    D02.540.505.760
    0 references
    RxNorm ID Béarla
    35302
    1 reference
    ráite i
    Global Substance Registration System Béarla
    UNII Béarla
    W36ZG6FT64
    dáta rochtana
    14 Feabhra 2018
    DrugBank ID Béarla
    00877
    1 reference
    ráite i
    DrugBank Béarla
    DrugBank ID Béarla
    00877
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Sirolimus (Béarla)
    dáta foilsithe
    17 Samhain 2015
    KNApSAcK ID Béarla
    C00018055
    0 references
    UNII Béarla
    MedlinePlus drug identifier Béarla
    a602026
    0 references
    PatientsLikeMe treatment ID Béarla
    sirolimus
    0 references
    NDF-RT ID Béarla
    N0000148624
    1 reference
    ráite i
    NDF-RT Béarla
    NDF-RT ID Béarla
    N0000148624
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    SIROLIMUS (Béarla)
    dáta rochtana
    19 Eanáir 2016
    Probes And Drugs ID Béarla
    PD003301
    0 references
    DrugCentral ID Béarla
    2446
    1 reference
    ráite i
    UniChem Béarla
    KEGG ID Béarla
    C07909
    1 reference
    ráite i
    ChEMBL Béarla
    ChEMBL ID Béarla
    CHEMBL413
    teanga an tsaothair nó an ainm
    Béarla
    teideal
    Sirolimus (Béarla)
    dáta rochtana
    19 Eanáir 2016
    LIPID MAPS ID Béarla
    LMPK06000003
    0 references
    PDB ligand ID Béarla
    RAP
    0 references
    DeCS ID Béarla
    33809
    0 references
    Freebase ID Béarla
    /m/02m01g
    1 reference
    ráite i
    Freebase Data Dumps Béarla
    dáta foilsithe
    28 Deireadh Fómhair 2013
    J-GLOBAL ID Béarla
    200907050996917166
    0 references
    Microsoft Academic ID Béarla
    2777921159
    0 references
    Nikkaji ID Béarla
    J137.896A
    0 references
    UNSPSC Code Béarla
    51201515
    0 references
    WikiProjectMed ID Béarla
    Sirolimus
    0 references
     
    cuir in eagar
    cuir in eagar
      cuir in eagar
        cuir in eagar
          cuir in eagar
            cuir in eagar
              cuir in eagar
                cuir in eagar
                  cuir in eagar
                  Aisghafa ó "https://www.wikidata.org/w/index.php?title=Q32089&oldid=2147243905"