Evolving catalytic antibodies in a phage-displayed combinatorial library (Q32063424)

6 July 2017

Evolving catalytic antibodies in a phage-displayed combinatorial library (English)

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6 July 2017

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Fujii I

1

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6 July 2017

Fukuyama S

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2

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6 July 2017

Iwabuchi Y

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3

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6 July 2017

Tanimura R

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4

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6 July 2017

1 May 1998

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6 July 2017

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6 July 2017

16

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6 July 2017

463-467

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6 July 2017

5

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https://scigraph.springernature.com/pub.10.1038/nbt0598-463

6 July 2017

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Phage display of a catalytic antibody to optimize affinity for transition-state analog binding

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Structural insights into the evolution of an antibody combining site

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Transition-state stabilization as a measure of the efficiency of antibody catalysis

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The dead-end elimination theorem and its use in protein side-chain positioning

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At the crossroads of chemistry and immunology: catalytic antibodies

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7 January 2021

From molecular diversity to catalysis: lessons from the immune system

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The immunological evolution of catalysis

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7 January 2021

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem

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7 January 2021

A mutagenesis study of a catalytic antibody

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7 January 2021

Catalytic antibody model and mutagenesis implicate arginine in transition-state stabilization

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7 January 2021

Site-directed mutagenesis of active site contact residues in a hydrolytic abzyme: evidence for an essential histidine involved in transition state stabilization

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7 January 2021

Canonical structures for the hypervariable regions of immunoglobulins

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7 January 2021

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

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7 January 2021

Correlation between Antigen-Combining-Site Structures and Functions within a Panel of Catalytic Antibodies Generated against a Single Transition State Analog

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7 January 2021

Crystal structure of a catalytic antibody with a serine protease active site

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7 January 2021

Revisiting ground-state and transition-state effects, the split-site model, and the "fundamentalist position" of enzyme catalysis

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7 January 2021

Use of binding energy in catalysis analyzed by mutagenesis of the tyrosyl-tRNA synthetase.

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7 January 2021

Three-dimensional structure of an antibody-antigen complex

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7 January 2021

Determinants of protein side-chain packing

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7 January 2021

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

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7 January 2021

Identifiers

DOI

10.1038/NBT0598-463

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Dimensions Publication ID

6 July 2017

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