F 12511, a novel ACAT inhibitor, and atorvastatin regulate endogenous hypercholesterolemia in a synergistic manner in New Zealand rabbits fed a casein-enriched diet (Q32063015)

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English	F 12511, a novel ACAT inhibitor, and atorvastatin regulate endogenous hypercholesterolemia in a synergistic manner in New Zealand rabbits fed a casein-enriched diet	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

6 July 2017

F 12511, a novel ACAT inhibitor, and atorvastatin regulate endogenous hypercholesterolemia in a synergistic manner in New Zealand rabbits fed a casein-enriched diet (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

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hypercholesterolemia

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author name string

Junquero D

1

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6 July 2017

Bruniquel F

2

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6 July 2017

N'Guyen X

3

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Europe PubMed Central

PubMed publication ID

6 July 2017

Autin JM

4

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Europe PubMed Central

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6 July 2017

Patoiseau JF

5

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Europe PubMed Central

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6 July 2017

Degryse AD

6

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6 July 2017

Colpaert FC

7

1 reference

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6 July 2017

Delhon A

8

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6 July 2017

publication date

1 March 2001

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6 July 2017

Atherosclerosis

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6 July 2017

155

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6 July 2017

1

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6 July 2017

131-142

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6 July 2017

Relation of plaque lipid composition and morphology to the stability of human aortic plaques.

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Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995.

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Molecular bases of the acute coronary syndromes

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Interactive role of infection, inflammation and traditional risk factors in atherosclerosis and coronary artery disease

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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

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Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.

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Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal

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Acyl-coenzyme A:cholesterol acyltransferase

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Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol

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Evidence that the initial up-regulation of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is an adaptive response that prevents cholesterol-induced cellular necrosis. Proposed role of an eventual failure of this response in

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Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death

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The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia

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Comparative effects of HMG-CoA reductase inhibitors on apo B production in the casein-fed rabbit: atorvastatin versus lovastatin

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7 January 2021

ACAT inhibition decreases LDL cholesterol in rabbits fed a cholesterol-free diet. Marked changes in LDL cholesterol without changes in LDL receptor mRNA abundance

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7 January 2021

Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol

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7 January 2021

Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets

1 reference

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7 January 2021

Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor

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7 January 2021

In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver

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Catabolism of low density lipoproteins by perfused rabbit livers: cholestyramine promotes receptor-dependent hepatic catabolism of low density lipoproteins

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Turnover of 125I-VLDL and 131I-LDL apolipoprotein B in rabbits fed diets containing casein or soy protein

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Role of dietary lysine, methionine, and arginine in the regulation of hypercholesterolemia in rabbits

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Tissue-specific expression and cholesterol regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice. Molecular cloning of mouse ACAT cDNA, chromosomal localization, and regulation of ACAT in vivo and in vitro

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Cholesterol metabolism in the adrenal cortex.

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Morphogenesis of a zone-specific adrenocortical cytotoxicity in guinea pigs administered PD 132301-2, an inhibitor of acyl-CoA:cholesterol acyltransferase

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7 January 2021

Subacute toxicity of a novel inhibitor of acyl-CoA: cholesterol acyltransferase in beagle dogs.

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ATP depletion is associated with cytotoxicity of a novel lipid regulator in guinea pig adrenocortical cells

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7 January 2021

Difference between normal and WHHL rabbits in susceptibility to the adrenal toxicity of an acyl-CoA:cholesterol acyltransferase inhibitor, FR145237

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7 January 2021

Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

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7 January 2021

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production

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7 January 2021

Lack of toxic effects of F 12511, a novel potent inhibitor of acyl-coenzyme A: cholesterol O-acyltransferase, on human adrenocortical cells in culture

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7 January 2021

HMG-CoA reductase and ACAT inhibitors act synergistically to lower plasma cholesterol and limit atherosclerotic lesion development in the cholesterol-fed rabbit

1 reference

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7 January 2021

Secretion of cholesteryl-ester-rich lipoproteins by the perfused livers of rabbits fed a wheat-starch-casein diet

1 reference

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7 January 2021

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10.1016/S0021-9150(00)00559-1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

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