Pharmacokinetics and biodistribution of a nucleotide-based thrombin inhibitor in rats (Q32058931)

6 July 2017

Pharmacokinetics and biodistribution of a nucleotide-based thrombin inhibitor in rats (English)

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6 July 2017

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Reyderman L

1

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PubMed ID

9647357

6 July 2017

Stavchansky S

series ordinal

2

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6 July 2017

1 June 1998

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6 July 2017

Pharmaceutical Research

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6 July 2017

15

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6 July 2017

6

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6 July 2017

904-910

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Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice

6 July 2017

1 reference

12 December 2020

Quantitative determination of short single-stranded oligonucleotides from blood plasma using capillary electrophoresis with laser-induced fluorescence

1 reference

12 December 2020

Disposition of the 14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats.

1 reference

12 December 2020

Association of antisense oligonucleotides with lipoproteins prolongs the plasma half-life and modifies the tissue distribution

1 reference

12 December 2020

A novel oligodeoxynucleotide inhibitor of thrombin. II. Pharmacokinetics in the cynomolgus monkey.

1 reference

12 December 2020

Biodistribution and metabolism of internally 3H-labeled oligonucleotides. I. Comparison of a phosphodiester and a phosphorothioate

1 reference

12 December 2020

A novel nucleotide-based thrombin inhibitor inhibits clot-bound thrombin and reduces arterial platelet thrombus formation

1 reference

12 December 2020

Biodistribution and metabolism of internally 3H-labeled oligonucleotides. II. 3',5'-blocked oligonucleotides

1 reference

12 December 2020

Tritium labeling of antisense oligonucleotides by exchange with tritiated water

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12 December 2020

Pilot study of the efficacy of a thrombin inhibitor for use during cardiopulmonary bypass

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12 December 2020

On-line HPLC electrospray mass spectrometry of phosphorothioate oligonucleotide metabolites

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12 December 2020

Renal uptake of an 18-mer phosphorothioate oligonucleotide

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12 December 2020

Substrate Specificity and Kinetics of Degradation of Antisense Oligonucleotides by a 3′ Exonuclease in Plasma

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12 December 2020

Organ distribution and stability of phosphorothioated oligodeoxyribonucleotides in mice

1 reference

12 December 2020

Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy

1 reference

12 December 2020

A novel oligodeoxynucleotide inhibitor of thrombin. I. In vitro metabolic stability in plasma and serum

1 reference

12 December 2020

In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits

1 reference

12 December 2020

Pharmacokinetics and tissue disposition of a chimeric oligodeoxynucleoside phosphorothioate in rats after intravenous administration

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1011980716659

1 reference

6 July 2017

1 reference

PubMed ID

9647357