The selective kappa-opioid receptor agonist U50,488H attenuates voluntary ethanol intake in the rat. (Q31965867)

5 July 2017

The selective kappa-opioid receptor agonist U50,488H attenuates voluntary ethanol intake in the rat. (English)

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5 July 2017

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S Lindholm

1

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5 July 2017

M Werme

series ordinal

2

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5 July 2017

S Brené

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3

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5 July 2017

J Franck

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4

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5 July 2017

language of work or name

English

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publication date

1 May 2001

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Behavioural Brain Research

5 July 2017

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5 July 2017

120

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5 July 2017

137-146

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5 July 2017

2

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Blockade of delta-opioid receptors in the nucleus accumbens prevents ethanol-induced stimulation of dopamine release

5 July 2017

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Ascending noradrenaline neurons from the pons and the medulla oblongata.

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The kappa-opioid U-50,488H suppresses the initiation of nocturnal spontaneous drinking in normally hydrated rats

1 reference

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Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats

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Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely moving rats.

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Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats

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Modulation of volitional ethanol intake in the rat by central delta-opioid receptors

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Importance of delta opioid receptors in maintaining high alcohol drinking

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Kappa opioid inhibition of morphine and cocaine self-administration in rats

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Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens.

1 reference

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Endogenous opioid systems and alcohol addiction

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The kappa agonists PD117302 and U50488 produce a biphasic effect on 24 hour food intake in the rat

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Involvement of mu-opioid receptors in alcohol drinking by alcohol-preferring AA rats

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Responding for oral ethanol after naloxone treatment by alcohol-preferring AA rats.

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The delta 2-opioid receptor antagonist naltriben selectively attenuates alcohol intake in rats bred for alcohol preference

1 reference

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Effect of mu opioid receptor blockade on alcohol intake in rats bred for high alcohol drinking.

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Kappa-opioid receptor agonist U50,488H modulates cocaine and morphine self-administration in drug-naive rats and mice

1 reference

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7 January 2021

Properties of a selective kappa agonist, U-50,488H

1 reference

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7 January 2021

U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats

1 reference

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A double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of oral nalmefene HCl for alcohol dependence

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Blockade of the morphine-induced increase in turnover of dopamine on the mesolimbic dopaminergic system by kappa-opioid receptor activation in mice

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Bremazocine reduces unrestricted free-choice ethanol self-administration in rats without affecting sucrose preference.

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Naltrexone in the treatment of alcoholism: a clinical review

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Opioid antagonists in the treatment of alcohol dependence: clinical efficacy and prevention of relapse

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Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists

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7 January 2021

Oral ethanol self-administration in the rat: effect of naloxone.

1 reference

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7 January 2021

U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

1 reference

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7 January 2021

Drugs to decrease alcohol drinking

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The limited access paradigm: description of one method

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Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes

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Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway

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Stereotaxic mapping of the monoamine pathways in the rat brain.

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Naltrexone in the treatment of alcohol dependence

1 reference

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Naltrexone blocks the post-shock increase of ethanol consumption

1 reference

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7 January 2021

Free-choice responding for ethanol versus water in alcohol preferring (P) and unselected Wistar rats is differentially modified by naloxone, bromocriptine, and methysergide.

1 reference

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7 January 2021

Opioid antagonist profile of SC nor-binaltorphimine in the formalin paw assay

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7 January 2021

Oral ethanol-reinforced responding in rhesus monkeys: effects of opioid antagonists selective for the mu-, kappa-, or delta-receptor

1 reference

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7 January 2021

10.1016/S0166-4328(00)00368-5

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5 July 2017

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