Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. (Q31917066)
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| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. |
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Discovery of 1-[3-(aminomethyl)phenyl]-N-3-fluoro-2'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa. (English)
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Pinto DJ
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Orwat MJ
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Wang S
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Fevig JM
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Quan ML
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Amparo E
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Cacciola J
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Rossi KA
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Alexander RS
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Smallwood AM
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Luettgen JM
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Liang L
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Aungst BJ
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Wright MR
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Knabb RM
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Wong PC
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Wexler RR
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Lam PY
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1 February 2001
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