Ribosome display and affinity maturation: from antibodies to single V-domains and steps towards cancer therapeutics (Q31874226)

4 July 2017

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title

Ribosome display and affinity maturation: from antibodies to single V-domains and steps towards cancer therapeutics (English)

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4 July 2017

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Irving RA

1

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4 July 2017

Coia G

2

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4 July 2017

Roberts A

3

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4 July 2017

Nuttall SD

4

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4 July 2017

Hudson PJ

5

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4 July 2017

1 February 2001

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Journal of Immunological Methods

4 July 2017

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4 July 2017

248

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4 July 2017

1-2

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4 July 2017

31-45

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Stable heterodimers from remodeling the domain interface of a homodimer using a phage display library

4 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody humanization using monovalent phage display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Translation rates of individual codons are not correlated with tRNA abundances or with frequencies of utilization in Escherichia coli

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Display technologies expand their horizons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Engineering antibodies for imaging and therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Use of mutator cells as a means for increasing production levels of a recombinant antibody directed against Hepatitis B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody VH domains as small recognition units

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Affinity improvement of single antibody VH domains: residues in all three hypervariable regions affect antigen binding

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody arrays for high-throughput screening of antibody-antigen interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Effects of substitutions in the binding surface of an antibody on antigen affinity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Rates of spontaneous mutation among RNA viruses

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Mutation rates among RNA viruses

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Cotranslational protein folding

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Identification of framework residues in a secreted recombinant antibody fragment that control production level and localization in Escherichia coli.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Beyond binding: using phage display to select for structure, folding and enzymatic activity in proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

High-affinity peptide ligands to prostate-specific antigen identified by polysome selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The disulfide bonds in antibody variable domains: effects on stability, folding in vitro, and functional expression in Escherichia coli.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Asphyxial brain injury--the role of the IGF system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Naturally occurring antibodies devoid of light chains

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

In vitro selection and evolution of functional proteins by using ribosome display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Comparison of Escherichia coli and rabbit reticulocyte ribosome display systems

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Selection of a human anti-progesterone antibody fragment from a transgenic mouse library by ARM ribosome display

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody phage display technology and its applications.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Recombinant antibody constructs in cancer therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Affinity maturation of recombinant antibodies using E. coli mutator cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Two amino acid mutations in an anti-human CD3 single chain Fv antibody fragment that affect the yield on bacterial secretion but not the affinity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The fibronectin type III domain as a scaffold for novel binding proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Cotranslational folding of globin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Solution properties of Escherichia coli-expressed VH domain of anti-neuraminidase antibody NC41

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Folding of an enzyme into an active conformation while bound as peptidyl-tRNA to the ribosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Cloning and expression of human V-genes derived from phage display libraries as fully assembled human anti-TNF alpha monoclonal antibodies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Enzymatic activity of the ribosome-bound nascent polypeptide

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

An in vitro polysome display system for identifying ligands from very large peptide libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Phage antibodies: filamentous phage displaying antibody variable domains

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Model systems to study the parameters determining the success of phage antibody selections on complex antigens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

In vitro virus: bonding of mRNA bearing puromycin at the 3'-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Disrupting the hydrophobic patches at the antibody variable/constant domain interface: improved in vivo folding and physical characterization of an engineered scFv fragment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Improvements in Immunoprecipitation of Specific Messenger RNA. Isolation of Highly Purified Conalbumin mRNA in High Yield

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Uncoupling translocation from translation: implications for transport of proteins across membranes

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibodies from Escherichia coli.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

New protein engineering approaches to multivalent and bispecific antibody fragments

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Error-prone retrotransposition: rime of the ancient mutators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Antibody scFv fragments without disulfide bonds made by molecular evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The mutant distribution of an RNA species replicated by Q beta replicase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

An antibody single-domain phage display library of a native heavy chain variable region: isolation of functional single-domain VH molecules with a unique interface.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

RNA-peptide fusions for the in vitro selection of peptides and proteins

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Totally in vitro protein selection using mRNA-protein fusions and ribosome display

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Structural analysis of the nurse shark (new) antigen receptor (NAR): molecular convergence of NAR and unusual mammalian immunoglobulins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Ribosome display: an in vitro method for selection and evolution of antibodies from libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

The RNA-dependent RNA polymerases of different members of the family Flaviviridae exhibit similar properties in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Structural correlates of an anticarcinoma antibody: identification of specificity-determining residues (SDRs) and development of a minimally immunogenic antibody variant by retention of SDRs only

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

CTLA-4, a negative regulator of T-lymphocyte activation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Making antibodies by phage display technology

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

Molecular evolution by staggered extension process (StEP) in vitro recombination

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-1759%2800%2900341-0

10.1016/S0022-1759(00)00341-0

7 January 2021

Identifiers

DOI

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4 July 2017

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