A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region (Q31621466)

3 July 2017

A negative cis-element regulates the level of enhancement by hypersensitive site 2 of the beta-globin locus control region (English)

1 reference

3 July 2017

Elnitski L

1

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3 July 2017

Li J

2

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3 July 2017

Noguchi CT

3

1 reference

3 July 2017

Miller W

4

1 reference

3 July 2017

Hardison R

5

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3 July 2017

language of work or name

English

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publication date

22 November 2000

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Journal of Biological Chemistry

3 July 2017

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3 July 2017

276

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3 July 2017

9

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3 July 2017

6289-6298

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The regulation of human globin gene switching

3 July 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Regulation of the beta-globin locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

The "beta-like-globin" gene domain in human erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A developmentally stable chromatin structure in the human beta-globin gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Erythroid-specific nuclease-hypersensitive sites flanking the human beta-globin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Looping versus linking: toward a model for long-distance gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Transcription complex stability and chromatin dynamics in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Synergism between hypersensitive sites confers long-range gene activation by the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Synergistic enhancement of globin gene expression by activator protein-1-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Conserved E boxes function as part of the enhancer in hypersensitive site 2 of the beta-globin locus control region. Role of basic helix-loop-helix proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Multiple elements in human beta-globin locus control region 5' HS 2 are involved in enhancer activity and position-independent, transgene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

The complete sequences of the galago and rabbit beta-globin locus control regions: extended sequence and functional conservation outside the cores of DNase hypersensitive sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

The world according to Maf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Isolation of cDNA encoding the human NF-E2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Molecular cloning of a putative novel human bZIP transcription factor on chromosome 17q22

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

In vivo protein-DNA interactions at the beta-globin gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Protein-DNA interactions in vivo of an erythroid-specific, human beta-globin locus enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A novel DNA-binding protein, HS2NF5, interacts with a functionally important sequence of the human beta-globin locus control region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the beta-globin locus control region. Domain opening and synergism between HS2 and HS3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Modulatory subdomains of the HS2 enhancer differentially regulate enhancer activity in erythroid cells at different developmental stages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Inducible transcription of five globin genes in K562 human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

HEL Cells: A New Human Erythroleukemia Cell Line with Spontaneous and Induced Globin Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Comparative analysis of the locus control region of the rabbit beta-like gene cluster: HS3 increases transient expression of an embryonic epsilon-globin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Derepression of mouse beta-major-globin gene transcription during erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Positive and negative regulatory elements of the rabbit embryonic epsilon-globin gene revealed by an improved multiple alignment program and functional analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Minichromosome assembly of non-integrated plasmid DNA transfected into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Molecular analysis of the human beta-globin locus activation region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Efficient and Reliable Transfection of Mouse Erythroleukemia Cells Using Cationic Lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Multiple Regulatory Elements in the 5′-Flanking Sequence of the Human ε-Globin Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

Erythropoietin-induced transcription at the murine beta maj-globin promoter. A central role for GATA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009624200

21 January 2018

Identifiers

DOI

10.1074/JBC.M009624200

1 reference

3 July 2017

1 reference