Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter. (Q31416109)

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8 November 2019

title

Stability and in vitro metabolism of dipeptide model prodrugs with affinity for the oligopeptide transporter (English)

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8 November 2019

10

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8 November 2019

author name string

E I Lepist

1

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8 November 2019

T Kusk

2

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8 November 2019

D H Larsen

3

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8 November 2019

D Andersen

4

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8 November 2019

S Frokjaer

5

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8 November 2019

M E Taub

6

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8 November 2019

P Veski

7

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8 November 2019

H Lennernäs

8

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8 November 2019

G Friedrichsen

9

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8 November 2019

language of work or name

English

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publication date

1 July 2000

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European Journal of Pharmaceutical Sciences

8 November 2019

published in

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volume

11

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8 November 2019

issue

1

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page(s)

43-50

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pGlu-L-Dopa-Pro: a tripeptide prodrug targeting the intestinal peptide transporter for absorption and tissue enzymes for conversion

8 November 2019

cites work

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Structural specificity of mucosal-cell transport and metabolism of peptide drugs: implication for oral peptide drug delivery

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Kinetic salt effect in pharmaceutical investigations.

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The effect of conformation on membrane permeability of an acyloxyalkoxy-linked cyclic prodrug of a model hexapeptide

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7 January 2021

Diketopiperazine formation, hydrolysis, and epimerization of the new dipeptide angiotensin-converting enzyme inhibitor RS-10085.

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Preformulation stability studies of the new dipeptide angiotensin-converting enzyme inhibitor RS-10029

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Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability

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7 January 2021

5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter

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7 January 2021

Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter

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7 January 2021

Structural requirements for interaction with the oligopeptide transporter in Caco-2 cells

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7 January 2021

Use of the peptide carrier system to improve the intestinal absorption of L-alpha-methyldopa: carrier kinetics, intestinal permeabilities, and in vitro hydrolysis of dipeptidyl derivatives of L-alpha-methyldopa

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7 January 2021

Rat jejunal permeability and metabolism of mu-selective tetrapeptides in gastrointestinal fluids from humans and rats

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7 January 2021

Characterization of fluids from the stomach and proximal jejunum in men and women.

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7 January 2021

Intestinal absorption of stable cyclic dipeptides by the oligopeptide transporter in rat

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7 January 2021

Stability, metabolism and transport of D-Asp(OBzl)-Ala--a model prodrug with affinity for the oligopeptide transporter.

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7 January 2021

10.1016/S0928-0987(00)00079-8

Identifiers

DOI

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8 November 2019

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