New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products (Q31156724)

14 August 2017

New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products (English)

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14 August 2017

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Byron Caughey

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14 August 2017

David A Kocisko

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14 August 2017

Gerald S Baron

2

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14 August 2017

Richard Rubenstein

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14 August 2017

Jiancao Chen

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14 August 2017

Salomon Kuizon

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1 October 2003

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77

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10288-10294

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19

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describes a project that uses

14 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC228499/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Inhibition of Protease-Resistant Prion Protein Accumulation In Vitro by Curcumin

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Potent inhibition of scrapie prion replication in cultured cells by bis-acridines

21 June 2018

1 reference

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Tetracyclines affect prion infectivity

21 June 2018

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Prevention of carcinogenesis by tea polyphenols

21 June 2018

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Cell culture models of transmissible spongiform encephalopathies

21 June 2018

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Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform

21 June 2018

1 reference

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Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies.

21 June 2018

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Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 June 2018

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Transmissible spongiform encephalopathies and prion protein interconversions

21 June 2018

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Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

21 June 2018

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Branched polyamines cure prion-infected neuroblastoma cells

21 June 2018

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Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains

21 June 2018

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Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

21 June 2018

1 reference

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Screening Congo Red and its analogues for their ability to prevent the formation of PrP-res in scrapie-infected cells

21 June 2018

1 reference

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Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures.

21 June 2018

1 reference

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Porphyrin and phthalocyanine antiscrapie compounds.

21 June 2018

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Prion protein and the transmissible spongiform encephalopathy diseases

21 June 2018

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Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein

21 June 2018

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Effectiveness of polyene antibiotics in treatment of transmissible spongiform encephalopathy in transgenic mice expressing Syrian hamster PrP only in neurons

21 June 2018

1 reference

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21 June 2018

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Wide distribution of [3H](-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue.

21 June 2018

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Doxycycline control of prion protein transgene expression modulates prion disease in mice

21 June 2018

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Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

21 June 2018

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Congo red prolongs the incubation period in scrapie-infected hamsters.

21 June 2018

1 reference

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Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 June 2018

1 reference

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Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

21 June 2018

1 reference

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A single hamster PrP amino acid blocks conversion to protease-resistant PrP in scrapie-infected mouse neuroblastoma cells.

21 June 2018

1 reference

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N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

21 June 2018

1 reference

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Chimeric prion protein expression in cultured cells and transgenic mice

21 June 2018

1 reference

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A solid-phase assay for identification of modulators of prion protein interactions

21 June 2018

1 reference

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A sensitive filter retention assay for the detection of PrP(Sc) and the screening of anti-prion compounds.

31 October 2018

1 reference

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Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs.

31 October 2018

1 reference

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[Prospects of the therapeutic approaches to Creutzfeldt-Jakob disease: a clinical trial of antimalarial, quinacrine]

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12970413

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.77.19.10288-10294.2003

1 reference

14 August 2017

1 reference

14 August 2017

1 reference