Neuroinflammation - using big data to inform clinical practice (Q31142833)

29 June 2017

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title

Neuroinflammation - using big data to inform clinical practice (English)

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29 June 2017

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Lars Fugger

3

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29 June 2017

Calliope A Dendrou

1

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29 June 2017

Gil McVean

series ordinal

2

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29 June 2017

language of work or name

English

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publication date

18 November 2016

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29 June 2017

Nature Reviews Neurology

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29 June 2017

12

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29 June 2017

12

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29 June 2017

685-698

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Microglia as neuroprotective, immunocompetent cells of the CNS.

29 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mechanisms underlying inflammation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Regulation of microglia activation and deactivation by nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The global burden of neurologic diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Biology: The big challenges of big data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The anatomical and cellular basis of immune surveillance in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Brain atrophy in clinically early relapsing-remitting multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Pathology of demyelinating diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The choreography of neuroinflammation in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

CD33 modulates TREM2: convergence of Alzheimer loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Schizophrenia risk from complex variation of complement component 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Complement and microglia mediate early synapse loss in Alzheimer mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Big data analytics in healthcare: promise and potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Big data analytics to improve cardiovascular care: promise and challenges

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Human Genome Project: Twenty-five years of big biology

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mutations in ADAR1, IFIH1, and RNASEH2B presenting as spastic paraplegia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Class II HLA interactions modulate genetic risk for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Disease networks. Uncovering disease-disease relationships through the incomplete interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Selecting causal genes from genome-wide association studies via functionally coherent subnetworks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genetic insights into common pathways and complex relationships among immune-mediated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 Variants in Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Frontotemporal dementia and its subtypes: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mutations of optineurin in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Exome sequencing supports a de novo mutational paradigm for schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

De novo mutations in schizophrenia implicate synaptic networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A polygenic burden of rare disruptive mutations in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A systematic survey of loss-of-function variants in human protein-coding genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genome engineering using the CRISPR-Cas9 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Efficient generation of astrocytes from human pluripotent stem cells in defined conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Interpreting noncoding genetic variation in complex traits and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genetic and epigenetic fine mapping of causal autoimmune disease variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The microglial sensome revealed by direct RNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Differential roles of microglia and monocytes in the inflamed central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Highly multiplexed simultaneous detection of RNAs and proteins in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A draft map of the human proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Mass-spectrometry-based draft of the human proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Cell type- and brain region-resolved mouse brain proteome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Deep phenotyping: The details of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genomic variation. Impact of regulatory variation from RNA to protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The virome in mammalian physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Host microbiota constantly control maturation and function of microglia in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Alterations of the human gut microbiome in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Putting big data to good use in neuroscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Making big data open: data sharing in neuroimaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The big data challenges of connectomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A multi-modal parcellation of human cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Big data from small data: data-sharing in the 'long tail' of neuroscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Learning from big health care data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A vision and a prescription for big data-enabled medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Weighing in on autoimmune disease: Big data tip the scale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A global reference for human genetic variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A review of approaches to identifying patient phenotype cohorts using electronic health records.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Participatory medicine: a driving force for revolutionizing healthcare

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Building the foundation for genomics in precision medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Imaging insights into basal ganglia function, Parkinson's disease, and dystonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Neuroimaging in amyotrophic lateral sclerosis: insights into structural and functional changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A genome-wide association study of brain lesion distribution in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Cervical cord lesion load is associated with disability independently from atrophy in MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Modeling disease severity in multiple sclerosis using electronic health records

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

21 January 2018

UK Biobank comes of age.

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

5 year mortality predictors in 498,103 UK Biobank participants: a prospective population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Big data in health care: using analytics to identify and manage high-risk and high-cost patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Online Prediction of Health Care Utilization in the Next Six Months Based on Electronic Health Record Information: A Cohort and Validation Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Bringing genome-wide association findings into clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Clinical development success rates for investigational drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The support of human genetic evidence for approved drug indications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Validating therapeutic targets through human genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFN-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

MSBase: an international, online registry and platform for collaborative outcomes research in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Risk of natalizumab-associated progressive multifocal leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

NSAID Use and Incident Cognitive Impairment in a Population-based Cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Effectiveness and cost-effectiveness of interferon beta and glatiramer acetate in the UK Multiple Sclerosis Risk Sharing Scheme at 6 years: a clinical cohort study with natural history comparator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Immune interventions in stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Amiloride Clinical Trial In Optic Neuritis (ACTION) protocol: a randomised, double blind, placebo controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease-like pathology and cognitive decline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Ustekinumab induction and maintenance therapy in refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Seven Questions for Personalized Medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Quantitative home-based assessment of Parkinson's symptoms: the SENSE-PARK feasibility and usability study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The mPower study, Parkinson disease mobile data collected using ResearchKit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Building global capacity for brain and nervous system disorders research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Creating value in health care through big data: opportunities and policy implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Setting value-based payment goals--HHS efforts to improve U.S. health care.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

The inevitable application of big data to health care

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Comparative effectiveness research and big data: balancing potential with legal and ethical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

A proposal to protect privacy of health information while accelerating comparative effectiveness research

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Cutting Edge: TREM-2 Attenuates Macrophage Activation

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1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

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1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Immunopathology of multiple sclerosis

31 March 2020

1 reference

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

31 March 2020

1 reference

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Human phenotyping on a population scale

31 March 2020

1 reference

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Increased exonic de novo mutation rate in individuals with schizophrenia

31 March 2020

1 reference

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Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2016.171

Human gut microbiome viewed across age and geography

31 March 2020

1 reference

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Demystifying disease, democratizing health care

31 March 2020

1 reference

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Customization of a Severity of Illness Score Using Local Electronic Medical Record Data

31 March 2020

1 reference

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Response to interferon-beta treatment in multiple sclerosis patients: a genome-wide association study

31 March 2020

1 reference

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Anti-CD20 antibody wows in multiple sclerosis

31 March 2020

1 reference

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Immunotherapy: immunological bullets against Alzheimer's disease

31 March 2020

1 reference

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Clinical utility of genetic and genomic services: a position statement of the American College of Medical Genetics and Genomics

31 March 2020

1 reference

12 December 2020

TNF neutralization in MS: results of a randomized, placebo-controlled multicenter study. The Lenercept Multiple Sclerosis Study Group and The University of British Columbia MS/MRI Analysis Group

1 reference

12 December 2020

The Multiple Sclerosis Performance Test (MSPT): an iPad-based disability assessment tool

1 reference

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Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial

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12 December 2020

10.1038/NRNEUROL.2016.171

Identifiers

DOI

1 reference

Dimensions Publication ID

29 June 2017

0 references

1 reference