Treatment of cognitive deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors (Q31116328)

29 June 2017

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title

Treatment of cognitive deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors (English)

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29 June 2017

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2

Daniel R Weinberger

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29 June 2017

José A Apud

1

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29 June 2017

1 January 2007

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29 June 2017

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29 June 2017

21

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29 June 2017

535-557

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29 June 2017

7

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https://scigraph.springernature.com/pub.10.2165/00023210-200721070-00002

29 June 2017

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Effects of dextroamphetamine on cognitive performance and cortical activation.

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12 December 2020

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12 December 2020

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Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited.

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Enzymatic O-methylation of epinephrine and other catechols.

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Dextroamphetamine enhances "neural network-specific" physiological signals: a positron-emission tomography rCBF study.

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Prefrontal and temporal blood flow in schizophrenia: resting and activation technetium-99m-HMPAO SPECT patterns in young neuroleptic-naive patients with acute disease.

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Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles.

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12 December 2020

No association between schizophrenia and polymorphisms in COMT in two large samples

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Cognitive improvement during Tolcapone treatment in Parkinson's disease.

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12 December 2020

Variations in extracellular monoamines in the prefrontal cortex and medial hypothalamus after modafinil administration: a microdialysis study in rats

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12 December 2020

Dopaminergic modulation of cortical function in patients with Parkinson's disease

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12 December 2020

Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors

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12 December 2020

Evoked extracellular dopamine in vivo in the medial prefrontal cortex.

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12 December 2020

New selective COMT inhibitors: useful adjuncts for Parkinson's disease?

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12 December 2020

Cortical dysfunction in schizophrenia during auditory word and tone working memory demonstrated by functional magnetic resonance imaging.

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12 December 2020

Catechol O-methyltransferase pharmacogenetics: photoaffinity labelling and western blot analysis of human liver samples

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12 December 2020

Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia.

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12 December 2020

Pieces of the schizophrenia puzzle fall into place

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Increased dopamine transmission in schizophrenia: relationship to illness phases

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12 December 2020

Catechol-O-methyltransferase activity: a determinant of levodopa response.

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12 December 2020

EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.

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12 December 2020

Tolcapone improves cognition and cortical information processing in normal human subjects

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12 December 2020

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The effects of combined prefrontal cortical and hippocampal damage on dopamine-related behaviors in rats.

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12 December 2020

Variations in catechol-O-methyltransferase activity in inbred strains of rats

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12 December 2020

Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.

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12 December 2020

The role of the regulatory enzymes of catecholamine synthesis in Parkinson's disease

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12 December 2020

Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.

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12 December 2020

Low frontal electroencephalographic coherence in neuroleptic-free schizophrenic patients

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12 December 2020

The functional architecture of the prefrontal cortex and schizophrenia

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12 December 2020

Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia.

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12 December 2020

Social disability and outcome in schizophrenic patients

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12 December 2020

Ro 40-7592: inhibition of COMT in rat brain and extracerebral tissues

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12 December 2020

Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia.

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12 December 2020

Cloning and Characterization of Human Placental Catechol--Methyltransferase cDNA

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12 December 2020

Human liver catechol-O-methyltransferase pharmacogenetics

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12 December 2020

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia

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12 December 2020

Cognitive predictors of psychosocial functioning outcome in schizophrenia: a follow-up study of subjects participating in a rehabilitation program.

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12 December 2020

Receptor activity and turnover of dopamine and noradrenaline after neuroleptics

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12 December 2020

Metabolism and excretion of tolcapone, a novel inhibitor of catechol-O-methyltransferase

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12 December 2020

Dopamine transporter immunoreactivity in monkey cerebral cortex: regional, laminar, and ultrastructural localization

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12 December 2020

Molecular cloning and characterization of rat liver catechol-O-methyltransferase

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12 December 2020

Linkage disequilibrium on the COMT gene in French schizophrenics and controls

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12 December 2020

Prefrontal cognitive deficits in patients with schizophrenia treated with atypical or conventional antipsychotics.

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12 December 2020

Effect of a novel catechol-O-methyltransferase inhibitor, nitecapone, on the metabolism of L-dopa in healthy volunteers

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12 December 2020

Behavioural and biochemical effects of dopamine and noradrenaline depletion within the medial prefrontal cortex of the rat

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12 December 2020

Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11

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12 December 2020

Aripiprazole increases dopamine but not noradrenaline and serotonin levels in the mouse prefrontal cortex

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12 December 2020

The principal features and mechanisms of dopamine modulation in the prefrontal cortex

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12 December 2020

Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction

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12 December 2020

Neonatal lesions of the medial temporal lobe disrupt prefrontal cortical regulation of striatal dopamine.

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12 December 2020

Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort.

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12 December 2020

Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice

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12 December 2020

The reduced neuropil hypothesis: a circuit based model of schizophrenia.

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12 December 2020

An in vivo study of dopamine release and metabolism in rat brain regions using intracerebral dialysis.

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12 December 2020

Sexual dimorphism of the catechol-O-methyltransferase gene in narcolepsy is associated with response to modafinil

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12 December 2020

A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition

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12 December 2020

Interaction between diffusion and Michaelis-Menten uptake of dopamine after iontophoresis in striatum.

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12 December 2020

10.2165/00023210-200721070-00002

Identifiers

DOI

1 reference

PubMed ID

17579498

Dimensions Publication ID

29 June 2017

0 references

1 reference

PubMed ID

17579498