Accumulation of wildtype and ALS-linked mutated VAPB impairs activity of the proteasome (Q31038125)

5 September 2017

Accumulation of wildtype and ALS-linked mutated VAPB impairs activity of the proteasome (English)

1 reference

amyotrophic lateral sclerosis

5 September 2017

1 reference

Isabelle Virard

2

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author name string

Anice Moumen

series ordinal

1

1 reference

PMCID

3187839

5 September 2017

Cédric Raoul

series ordinal

3

1 reference

PMCID

3187839

5 September 2017

language of work or name

English

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publication date

5 October 2011

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5 September 2017

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5 September 2017

6

1 reference

5 September 2017

10

1 reference

5 September 2017

e26066

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Creative Commons Attribution 4.0 International

5 September 2017

start time

5 October 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3187839/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ALS-linked P56S-VAPB, an aggregated loss-of-function mutant of VAPB, predisposes motor neurons to ER stress-related death by inducing aggregation of co-expressed wild-type VAPB.

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Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport

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VAPB interacts with and modulates the activity of ATF6.

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The proteasome maturation protein POMP facilitates major steps of 20S proteasome formation at the endoplasmic reticulum

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Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates.

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Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8)

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21 June 2018

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FAT10, a ubiquitin-independent signal for proteasomal degradation

21 June 2018

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Real-time monitoring of ubiquitination in living cells by BRET.

21 June 2018

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 June 2018

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Coupling of ER exit to microtubules through direct interaction of COPII with dynactin

21 June 2018

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Differential regulation of endoplasmic reticulum structure through VAP-Nir protein interaction

21 June 2018

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A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

21 June 2018

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Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

21 June 2018

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Protein aggregation in motor neurone disorders.

21 June 2018

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21 June 2018

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 June 2018

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ERG30, a VAP-33-related protein, functions in protein transport mediated by COPI vesicles

21 June 2018

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21 June 2018

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Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

21 June 2018

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A proteolytic pathway that recognizes ubiquitin as a degradation signal

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187839

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187839

In vivo half-life of a protein is a function of its amino-terminal residue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3187839

Accumulation of human SOD1 and ubiquitinated deposits in the spinal cord of SOD1G93A mice during motor neuron disease progression correlates with a decrease of proteasome.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

Amyotrophic lateral sclerosis mutant vesicle-associated membrane protein-associated protein-B transgenic mice develop TAR-DNA-binding protein-43 pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

The ALS8-associated mutant VAPB(P56S) is resistant to proteolysis in neurons

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0026066

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

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Chaperone-assisted assembly of the proteasome core particle.

21 January 2018

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Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

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Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

21 January 2018

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21 January 2018

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Neuropathology with clinical correlations of sporadic amyotrophic lateral sclerosis: 102 autopsy cases examined between 1962 and 2000.

25 November 2018

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KDEL-cargo regulates interactions between proteins involved in COPI vesicle traffic: measurements in living cells using FRET

25 November 2018

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Accelerated transport and maturation of lysosomal α–galactosidase A in Fabry lymphoblasts by an enzyme inhibitor

25 November 2018

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12 December 2020

Expression of ubiquitin and proteasome in motorneurons and astrocytes of spinal cords from patients with amyotrophic lateral sclerosis

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12 December 2020

A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum

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12 December 2020

Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin

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12 December 2020

Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells

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12 December 2020

10.1371/JOURNAL.PONE.0026066

Identifiers

DOI

1 reference

5 September 2017

0 references

1 reference

5 September 2017

1 reference

PMCID

3187839