Bioprospecting microbial natural product libraries from the marine environment for drug discovery (Q30985377)

28 June 2017

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title

Bioprospecting microbial natural product libraries from the marine environment for drug discovery (English)

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28 June 2017

marine natural product

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Xiangyang Liu

1

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28 June 2017

Elizabeth Ashforth

2

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28 June 2017

Biao Ren

3

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28 June 2017

Fuhang Song

4

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28 June 2017

Huanqin Dai

5

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28 June 2017

Mei Liu

6

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28 June 2017

Jian Wang

7

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28 June 2017

Qiong Xie

8

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28 June 2017

Lixin Zhang

9

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28 June 2017

7 July 2010

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The Journal of Antibiotics

28 June 2017

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28 June 2017

63

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28 June 2017

415-422

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28 June 2017

8

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Microbial drug discovery: 80 years of progress

28 June 2017

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https://api.crossref.org/works/10.1038%2FJA.2010.56

Bioactive microbial metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Environmental genome shotgun sequencing of the Sargasso Sea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Actinomycetes for marine drug discovery isolated from mangrove soils and plants in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marine actinobacteria: new opportunities for natural product search and discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

New drugs from marine microbes: the tide is turning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marine actinomycete diversity and natural product discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Diversifying microbial natural products for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Exploring novel bioactive compounds from marine microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Discovery and development of the anticancer agent salinosporamide A (NPI-0052).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Natural products as sources of new drugs over the last 25 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

The impact of natural products upon modern drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marine pharmacology in 2005-2006: antitumour and cytotoxic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Merging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Natural products as leads to anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

ChemGPS-NP: tuned for navigation in biologically relevant chemical space

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Charting biologically relevant chemical space: a structural classification of natural products (SCONP)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

The evolving role of natural products in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

A review of high throughput technology for the screening of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marine natural product libraries for high-throughput screening and rapid drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Renaissance in antibacterial discovery from actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Actinomadura flavalba sp. nov., an endophytic actinomycete isolated from leaves of Maytenus austroyunnanensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Actinopolymorpha cephalotaxi sp. nov., a novel actinomycete isolated from rhizosphere soil of the plant Cephalotaxus fortunei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Aidingimonas halophila gen. nov., sp. nov., a moderately halophilic bacterium isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Amycolatopsis halophila sp. nov., a halophilic actinomycete isolated from a salt lake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Amycolicicoccus subflavus gen. nov., sp. nov., an actinomycete isolated from a saline soil contaminated by crude oil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Bacillus neizhouensis sp. nov., a halophilic marine bacterium isolated from a sea anemone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Dietzia schimae sp. nov. and Dietzia cercidiphylli sp. nov., from surface-sterilized plant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Georgenia halophila sp. nov., a halophilic actinobacterium isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Glycomyces endophyticus sp. nov., an endophytic actinomycete isolated from the root of Carex baccans Nees

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Glycomyces scopariae sp. nov. and Glycomyces mayteni sp. nov., isolated from medicinal plants in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Gracilibacillus saliphilus sp. nov., a moderately halophilic bacterium isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Halobacillus salsuginis sp. nov., a moderately halophilic bacterium from a subterranean brine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Haloglycomyces albus gen. nov., sp. nov., a halophilic, filamentous actinomycete of the family Glycomycetaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Halomonas zhanjiangensis sp. nov., a halophilic bacterium isolated from a sea urchin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Herbidospora osyris sp. nov., isolated from surface-sterilized tissue of Osyris wightiana Wall. ex Wight

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isoptericola jiangsuensis sp. nov., a chitin-degrading bacterium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Jeotgalicoccus huakuii sp. nov., a halotolerant bacterium isolated from seaside soil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Jeotgalicoccus marinus sp. nov., a marine bacterium isolated from a sea urchin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Jiangella alba sp. nov., an endophytic actinomycete isolated from the stem of Maytenus austroyunnanensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Kineosporia mesophila sp. nov., isolated from surface-sterilized stems of Tripterygium wilfordii

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Kocuria halotolerans sp. nov., an actinobacterium isolated from a saline soil in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marinactinospora thermotolerans gen. nov., sp. nov., a marine actinomycete isolated from a sediment in the northern South China Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marinococcus luteus sp. nov., a halotolerant bacterium isolated from a salt lake, and emended description of the genus Marinococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Micrococcus endophyticus sp. nov., isolated from surface-sterilized Aquilaria sinensis roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Micrococcus yunnanensis sp. nov., a novel actinobacterium isolated from surface-sterilized Polyspora axillaris roots

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Nocardiopsis litoralis sp. nov., a halophilic marine actinomycete isolated from a sea anemone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Nonomuraea antimicrobica sp. nov., an endophytic actinomycete isolated from a leaf of Maytenus austroyunnanensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Paracoccus saliphilus sp. nov., a halophilic bacterium isolated from a saline soil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Paraliobacillus quinghaiensis sp. nov., isolated from salt-lake sediment in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Pigmentiphaga litoralis sp. nov., a facultatively anaerobic bacterium isolated from a tidal flat sediment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Plantactinospora mayteni gen. nov., sp. nov., a member of the family Micromonosporaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Pontibacillus halophilus sp. nov., a moderately halophilic bacterium isolated from a sea urchin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Pontibacillus litoralis sp. nov., a facultatively anaerobic bacterium isolated from a sea anemone, and emended description of the genus Pontibacillus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Prauserella salsuginis sp. nov., Prauserella flava sp. nov., Prauserella aidingensis sp. nov. and Prauserella sediminis sp. nov., isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Pseudonocardia endophytica sp. nov., isolated from the pharmaceutical plant Lobelia clavata

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Psychroflexus sediminis sp. nov., a mesophilic bacterium isolated from salt lake sediment in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Rhodococcus jialingiae sp. nov., an actinobacterium isolated from sludge of a carbendazim wastewater treatment facility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Saccharopolyspora gloriosae sp. nov., an endophytic actinomycete isolated from the stem of Gloriosa superba L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Saccharopolyspora halophila sp. nov., a novel halophilic actinomycete isolated from a saline lake in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Saccharopolyspora qijiaojingensis sp. nov., a halophilic actinomycete isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Saccharopolyspora tripterygii sp. nov., an endophytic actinomycete isolated from the stem of Tripterygium hypoglaucum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Salinicoccus albus sp. nov., a halophilic bacterium from a salt mine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Salinimicrobium terrae sp. nov., isolated from saline soil, and emended description of the genus Salinimicrobium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Sciscionella marina gen. nov., sp. nov., a marine actinomycete isolated from a sediment in the northern South China Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Stackebrandtia albiflava sp. nov. and emended description of the genus Stackebrandtia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Streptomonospora amylolytica sp. nov. and Streptomonospora flavalba sp. nov., two novel halophilic actinomycetes isolated from a salt lake

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Streptomyces artemisiae sp. nov., isolated from surface-sterilized tissue of Artemisia annua L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Streptomyces nanshensis sp. nov., isolated from the Nansha Islands in the South China Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Streptomyces sedi sp. nov., isolated from surface-sterilized roots of Sedum sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Streptomyces xinghaiensis sp. nov., isolated from marine sediment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Verrucosispora lutea sp. nov., isolated from a mangrove sediment sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Virgibacillus sediminis sp. nov., a moderately halophilic bacterium isolated from a salt lake in China

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Yimella lutea gen. nov., sp. nov., a novel actinobacterium of the family Dermacoccaceae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Zhihengliuella alba sp. nov., and emended description of the genus Zhihengliuella

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Diversity of actinomycetes isolated from Challenger Deep sediment (10,898 m) from the Mariana Trench.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Proximicin A, B and C, novel aminofuran antibiotic and anticancer compounds isolated from marine strains of the actinomycete Verrucosispora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Mars-like soils in the Atacama Desert, Chile, and the dry limit of microbial life

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isolating "uncultivable" microorganisms in pure culture in a simulated natural environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Widespread and persistent populations of a major new marine actinomycete taxon in ocean sediments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Diversity of cultivable actinobacteria in geographically widespread marine sediments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Cultivation of the ubiquitous SAR11 marine bacterioplankton clade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Genome Streamlining in a Cosmopolitan Oceanic Bacterium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

High-throughput methods for culturing microorganisms in very-low-nutrient media yield diverse new marine isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Tapping into microbial diversity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

A novel approach for high throughput cultivation assays and the isolation of planktonic bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Specific detection, isolation, and characterization of selected, previously uncultured members of the freshwater bacterioplankton community

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Cultivating the uncultured

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Metaproteomics: a new approach for studying functional microbial ecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Metagenomics-based drug discovery and marine microbial diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Novel approaches to developing new antibiotics for bacterial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Metagenomic approaches to exploit the biotechnological potential of the microbial consortia of marine sponges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Genetically modified bacterial strains and novel bacterial artificial chromosome shuttle vectors for constructing environmental libraries and detecting heterologous natural products in multiple expression hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Metagenomic gene discovery: past, present and future.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Big effects from small changes: possible ways to explore nature's chemical diversity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

A method for the selection of production media for actinomycete strains based on their metabolite HPLC profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isolation, structure, and antibacterial activities of lucensimycins D-G, discovered from Streptomyces lucensis MA7349 using an antisense strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Amycolatopsis marina sp. nov., an actinomycete isolated from an ocean sediment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Prauserella marina sp. nov., isolated from ocean sediment of the South China Sea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7, 22-diene-3 beta, 5 alpha, 6 beta-triol, with new activities from the marine-derived fungus Trichoderma sp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Trichodermaketones A-D and 7-O-methylkoninginin D from the marine fungus Trichoderma koningii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Distribution of biosurfactant-producing bacteria in undisturbed and contaminated arid Southwestern soils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

A novel actinomycete strain de-replication approach based on the diversity of polyketide synthase and nonribosomal peptide synthetase biosynthetic pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Rapid screening and dereplication of bacterial isolates from marine sponges of the sula ridge by intact-cell-MALDI-TOF mass spectrometry (ICM-MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Computer-assisted numerical analysis of colour-group data for dereplication of streptomycetes for bioprospecting and ecological purposes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Phenotypic taxonomy and metabolite profiling in microbial drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Dereplication of pentacyclic triterpenoids in plants by GC-EI/MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Fungal metabolite screening: database of 474 mycotoxins and fungal metabolites for dereplication by standardised liquid chromatography-UV-mass spectrometry methodology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

A rapid and facile method for the dereplication of purified natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Evolving trends in the dereplication of natural product extracts. 2. The isolation of chrysaibol, an antibiotic peptaibol from a New Zealand sample of the mycoparasitic fungus Sepedonium chrysospermum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Marine molecular biology: an emerging field of biological sciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Ribosomal RNA-targeted nucleic acid probes for studies in microbial ecology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Statistical approaches for estimating actinobacterial diversity in marine sediments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

New primers for the class Actinobacteria: application to marine and terrestrial environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Biogeography of bacteria associated with the marine sponge Cymbastela concentrica

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Host specificity in marine sponge-associated bacteria, and potential implications for marine microbial diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Sponge-associated microorganisms: evolution, ecology, and biotechnological potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

An update of the structure and 16S rRNA gene sequence-based definition of higher ranks of the class Actinobacteria, with the proposal of two new suborders and four new families and emended descriptions of the existing higher taxa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Daptomycin: mechanisms of action and resistance, and biosynthetic engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Discovery of FabH/FabF inhibitors from natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Accelerated Dereplication of Natural Products, Supported by Reference Libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Isolation and phylogenetic analysis of bacteria with antimicrobial activities from the Mediterranean sponges Aplysina aerophoba and Aplysina cavernicola

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJA.2010.56

Evaluation of Q-TOF-MS/MS and multiple stage IT-MSn for the dereplication of flavonoids and related compounds in crude plant extracts

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1 reference

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New PCR Primers for the Screening of NRPS and PKS-I Systems in Actinomycetes: Detection and Distribution of These Biosynthetic Gene Sequences in Major Taxonomic Groups

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1 reference

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Marine natural products

1 reference

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7 January 2021

Efficient approach to fluvirucins B2-B5, Sch 38518, and Sch 39185. First synthesis of their aglycon, via CM and RCM reactions

1 reference

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7 January 2021

Dereplication for biotechnology screening: PyMS analysis and PCR-RFLP-SSCP (PRS) profiling of 16S rRNA genes of marine and terrestrial actinomycetes

1 reference

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7 January 2021

LC-NMR: a new tool to expedite the dereplication and identification of natural products

1 reference

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7 January 2021

Molecular formula analysis by an MS/MS/MS technique to expedite dereplication of natural products

1 reference

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7 January 2021

Evolving trends in the dereplication of natural product extracts: new methodology for rapid, small-scale investigation of natural product extracts

1 reference

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7 January 2021

1 reference

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Physicochemical properties of antibacterial compounds: implications for drug discovery

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7 January 2021

Identifiers

DOI

10.1038/JA.2010.56

1 reference

Dimensions Publication ID

28 June 2017

0 references

1 reference