Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development (Q30890487)

14 October 2017

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title

Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development (English)

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matrix-assisted laser desorption/ionization

14 October 2017

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4

Brendan Prideaux

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14 October 2017

Eric G Solon

1

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14 October 2017

Alain Schweitzer

series ordinal

2

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14 October 2017

Markus Stoeckli

series ordinal

3

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14 October 2017

language of work or name

English

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publication date

17 November 2009

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14 October 2017

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14 October 2017

12

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14 October 2017

1

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14 October 2017

11-26

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https://scigraph.springernature.com/pub.10.1208/s12248-009-9158-4

14 October 2017

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cites work

Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

A new dynamic in mass spectral imaging of single biological cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

PET and macro- and microautoradiographic studies combined with immunohistochemistry for monitoring rat intestinal ulceration and healing processes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

MS/MS methodology to improve subcellular mapping of cholesterol using TOF-SIMS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Desorption electrospray ionization mass spectrometry: Imaging drugs and metabolites in tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Nanoparticle-assisted laser desorption/ionization based mass imaging with cellular resolution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Imaging mass spectrometry.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Secondary ion MS imaging to relatively quantify cholesterol in the membranes of individual cells from differentially treated populations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Localization of sphingomyelin in cholesterol domains by imaging mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Fluorescence imaging in vivo: recent advances

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Imaging TOF-SIMS of rat kidney prepared by high-pressure freezing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

An investigation of enhanced secondary ion emission under Au(n)+ (n = 1-7) bombardment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Subcellular imaging mass spectrometry of brain tissue.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

MALDI mass spectrometric imaging of biological tissue sections

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

High-spatial resolution mass spectrometric imaging of peptide and protein distributions on a surface

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Gold nanoparticles as selective and concentrating probes for samples in MALDI MS analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Sample metallization for performance improvement in desorption/ionization of kilodalton molecules: quantitative evaluation, imaging secondary ion MS, and laser ablation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Electron microscopic radioautography of thin sections: the Golgi zone as a site of protein concentration in pancreatic acinar cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Sulfate-sulfur metabolism in the rat fetus as indicated by sulfur-35.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Whole-body autoradiography in drug discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Fluorescent lipid probes: some properties and applications (a review).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Cation-chromatin binding as shown by ion microscopy is essential for the structural integrity of chromosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Organic ion imaging of biological tissue with secondary ion mass spectrometry and matrix-assisted laser desorption/ionization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Quantitative whole-body radioluminography-future strategy for balance and tissue distribution studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Quantitative whole-body autoradiography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Subcellular imaging by dynamic SIMS ion microscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Techniques and application of microscopic radioautography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Radioluminography for quantitative autoradiography of 14C.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Progressive application of autoradiography in pharmacokinetic and metabolic studies for the development of new drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Applications of secondary ion mass spectrometry (SIMS) in biological research: a review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Quantitative film autoradiography for tritium: methodological considerations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

The use of measurements of radiographic response of x-ray films in quantitative and semiquantitative whole body autoradiography.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Why is SIMS underused in chemical and biological analysis? Challenges and opportunities

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Biodistribution and plasma protein binding of zoledronic acid

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Transfollicular delivery of linoleic acid in human scalp skin: permeation study and microautoradiographic analysis

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Lipid imaging of human skeletal muscle using TOF-SIMS with bismuth cluster ion as a primary ion source.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Liquid microjunction surface sampling probe electrospray mass spectrometry for detection of drugs and metabolites in thin tissue sections

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Higher sensitivity secondary ion mass spectrometry of biological molecules for high resolution, chemically specific imaging.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

High-resolution TOF-SIMS imaging of eukaryotic cells preserved in a trehalose matrix.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Receptor microscopic autoradiography for the study of percutaneous absorption, in vivo skin penetration, and cellular-intercellular deposition

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Quantitative whole-body autoradiography in the pharmaceutical industry. Survey results on study design, methods, and regulatory compliance.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

(18)F-FDG and (18)F-FET uptake in experimental soft tissue infection

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811645

Studies on the distribution and fate of S35-labelled benzylpenicillin in the body

25 November 2018

1 reference

12 December 2020

Accumulation and retention of mercury in the mouse. I. An autoradiographic study after a single intravenous injection of mercuric chloride

1 reference

12 December 2020

A novel quantitative method for determining the biodistribution of radiolabeled xenobiotics using whole-body cryosectioning and autoradioluminography

1 reference

12 December 2020

Simplified liquid emulsion radioautography

1 reference

12 December 2020

A simple method for the quantitation of 14C-whole-body autoradiograms

1 reference

12 December 2020

VACUUM FREEZE DRYING OF FROZEN SECTIONS FOR DRY-MOUNTING, HIGH-RESOLUTION AUTORADIOGRAPHY

1 reference

12 December 2020

Quantitative distribution studies in animals: cross-validation of radioluminography versus liquid-scintillation measurement

1 reference

12 December 2020

Changes in regional renal blood flow after unilateral nephrectomy using the techniques of autoradiography and microautoradiography

1 reference

12 December 2020

A quantitative method for measuring radioactivity in tissues sectioned for whole-body autoradiography

1 reference

12 December 2020

A method for locating radioactive elements in tissues by covering histological sections with a photographic emulsion

1 reference

12 December 2020

In vitro micro-autoradiography of atrial natriuretic peptide in biopsy specimens from patients with renal diseases

1 reference

12 December 2020

AUTORADIOGRAPHY OF SOLUBLE LABELLED COMPOUNDS

1 reference

12 December 2020

A new approach to positron emission tomography

1 reference

12 December 2020

Utility of whole-body autoradioluminography in drug discovery for the quantification of tritium-labeled drug candidates

1 reference

12 December 2020

[The quantitative determination of the distribution of S35-sulfate in mice using autoradiography]

1 reference

12 December 2020

Application of macroscopic autoradiography to large animals in veterinary pharmacokinetics: the distribution of sodium selenite labelled with 75Se in the pig

1 reference

12 December 2020

A poly[methyl-14C]methacrylate source for use in whole-body autoradiography and beta-radiography

1 reference

12 December 2020

Localization of lipids in the aortic wall with imaging TOF-SIMS

1 reference

12 December 2020

A New Method of Macroautoradiography

1 reference

12 December 2020

10.1208/S12248-009-9158-4

Identifiers

DOI

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Dimensions Publication ID

14 October 2017

1007622063

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Fatcat ID

release_rjzv5knyvrerll34nnizkczluq

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Fatcat

https://api.fatcat.wiki/v0/release/rjzv5knyvrerll34nnizkczluq

24 November 2022

mapped directly with Wikidata item

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14 October 2017

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